[en] Seven healthy male subjects underwent a treadmill incremental work test in control conditions and during an intravenous epinephrine infusion (10 micrograms/min). At all exercise intensities, epinephrine increased heart rate, ventilation, respiratory quotient and plasma lactate levels without significant changes in oxygen consumption. Under epinephrine infusion, the "anaerobic threshold", considered as the critical intensity at which ventilation began to increase non linearly with oxygen consumption, appeared at a lower intensity and for a higher plasma lactate level than in control conditions. We conclude that the hyperventilation threshold does not necessarily reflect a muscular hypoxia. It could be due to an effect of catecholamines on peripheral chemoreceptors, maybe by alpha-adrenergic vasoconstriction in the carotid bodies.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Scheen, André ; Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale
Lemaire, Philippe ; Université de Liège - ULiège > CSL (Centre Spatial de Liège)
Language :
French
Title :
Abaissement du seuil d'hyperventilation par perfusion intraveineuse d'adrenaline lors d'un exercice triangulaire.
Alternative titles :
[fr] A reduction in the hyperventilation threshold by intravenous infusion of adrenaline in the treadmill exercise
Publication date :
1983
Journal title :
Archives Internationales de Physiologie et de Biochimie