Article (Scientific journals)
Un virus tapi dans l'ombre : les bases moleculaires de la latence du VIH-1 - Partie I : la physiologie de la latence du VIH-1.
Schwartz, Christian; Le Douce, Valentin; Cherrier, Thomas et al.
2010In MS. Medecine Sciences, 26 (2), p. 159-63
Peer Reviewed verified by ORBi
 

Files


Full Text
[Molecular basis of HIV-1 latency - part I physiology of HIV-1 latency]..pdf
Publisher postprint (251.56 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
DNA, Viral/genetics; Epigenesis, Genetic; Gene Expression Regulation, Viral; HIV Infections/virology; HIV-1/genetics/physiology; Host-Pathogen Interactions; Humans; Microglia/virology; Proviruses/genetics/physiology; RNA, Viral/genetics; Transcription, Genetic; Virus Integration; Virus Latency/genetics/physiology
Abstract :
[en] The introduction of the highly active antiretroviral therapy (HAART) in 1996 has greatly extended survival and raised hopes for the eradication of HIV-1. Unfortunately, the optimism declined by revealing the existence of latent HIV-1 reservoirs in cells targeted by the virus. The long-lived HIV-1 reservoirs constitute a major obstacle to the eradication of HIV-1. Understanding the molecular mechanisms of virus latency is essential for efficient therapeutic intervention against the virus.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Schwartz, Christian
Le Douce, Valentin
Cherrier, Thomas ;  Université de Liège - ULiège > GIGA-Research
Redel, Laetitia
Marban, Celine
Aunis, Dominique
Rohr, Olivier
Language :
French
Title :
Un virus tapi dans l'ombre : les bases moleculaires de la latence du VIH-1 - Partie I : la physiologie de la latence du VIH-1.
Alternative titles :
[en] Molecular basis of HIV-1 latency - part I: physiology of HIV-1 latency
Publication date :
2010
Journal title :
MS. Medecine Sciences
ISSN :
0767-0974
eISSN :
1958-5381
Publisher :
Editions EDK, France
Volume :
26
Issue :
2
Pages :
159-63
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 25 January 2013

Statistics


Number of views
198 (2 by ULiège)
Number of downloads
279 (2 by ULiège)

Scopus citations®
 
7
Scopus citations®
without self-citations
5
OpenCitations
 
8

Bibliography


Similar publications



Contact ORBi