Reference : Indolomonoterpenic alkaloids from Strychnos icaja roots
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
Life sciences : Phytobiology (plant sciences, forestry, mycology...)
http://hdl.handle.net/2268/13897
Indolomonoterpenic alkaloids from Strychnos icaja roots
English
Philippe, Geneviève mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
De Mol, Patrick mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Microbiologie médicale et virologie médicale]
Zeches-Hanrot, M. [> > > >]
Nuzillard, J. M. [> > > >]
Tits, M. H. [> > > >]
Angenot, Luc mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Frederich, Michel mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Feb-2003
Phytochemistry
Pergamon-Elsevier Science Ltd
62
4
623-629
Yes (verified by ORBi)
International
0031-9422
Oxford
[en] Loganiaceae ; Strychnos icaja ; indolomonoterpenic alkaloid ; strychnogucine C ; protostrychnine ; strychnohexamine ; Plasmodium falciparum
[en] In the course of our search for new antiplasmodial alkaloids from Strychnos icaja, we have isolated five alkaloids: three monomers, protostrychnine and genostrychnine, previously described in Strychnos nux-vomica, pseudostrychnine, already found in the leaves of the plant, a new bisindolic alkaloid, named strychnogucine C, and the first naturally occurring trimeric indolomonoterpenic alkaloid: strychnohexamine. This latter trimeric alkaloid presented an antiplasmodial activity against the FCA Plasmodium falciparum line near I muM. (C) 2002 Elsevier Science Ltd. All rights reserved.
http://hdl.handle.net/2268/13897

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