Reference : Main Glucosidase Conversion Products of the Gluco-Alkaloids Dolichantoside and Palicoside
Scientific journals : Article
Human health sciences : Pharmacy, pharmacology & toxicology
Life sciences : Phytobiology (plant sciences, forestry, mycology...)
http://hdl.handle.net/2268/13890
Main Glucosidase Conversion Products of the Gluco-Alkaloids Dolichantoside and Palicoside
English
Brandt, V. [> > > >]
Tits, Monique mailto [Université de Liège - ULg > Département de pharmacie > Phytochimie et phytothérapie >]
Penelle, J. [> > > >]
Frederich, Michel mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Angenot, Luc mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Jul-2001
Phytochemistry
57
5
653-9
Yes (verified by ORBi)
International
0031-9422
[en] The enzymatic glucose cleavage of palicoside revealed the biosynthetic pathway to akagerine, whereas the conversion of dolichantoside led to a new quaternary heteroyohimbine alkaloid named N(b)-methyl-21-beta-hydroxy-mayumbine. The hypothetical models of reactions occurring after the conversion of both substrates are proposed. Dolichantoside and palicoside, as well as Strychnos mellodora stem bark crude ethanol extract, exhibit significant antimycotic activity against human pathogens in presence of specific glucosidase.
http://hdl.handle.net/2268/13890

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