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| Reference : Quantitative analysis of strychnine and brucine in Strychnos nux-vomica using H-1-NMR |
| Scientific journals : Article | |||
| Human health sciences : Pharmacy, pharmacology & toxicology Physical, chemical, mathematical & earth Sciences : Chemistry Life sciences : Phytobiology (plant sciences, forestry, mycology...) | |||
| http://hdl.handle.net/2268/13879 | |||
| Quantitative analysis of strychnine and brucine in Strychnos nux-vomica using H-1-NMR | |
| English | |
Frederich, Michel  [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >] | |
| Choi, Y. H. [> > > >] | |
| Verpoorte, R. [> > > >] | |
| Dec-2003 | |
| Planta Medica | |
| Georg Thieme Verlag Kg | |
| 69 | |
| 12 | |
| 1169-1171 | |
| International | |
| 0032-0943 | |
| Stuttgart | |
| [en] A quantitative analysis using H-1-NMR (Q-NMR) has been developed for the determination of strychnine and brucine in Strychnos nux-vomica seeds and stems. The advantages of the method are that no reference alkaloids are needed for calibration curves, the quantification could be directly realized on a crude extract, strychnine and brucine could easily be distinguished, an overall profile of the preparation (including non alkaloid compounds) could be directly obtained, and a very significant time-gain could be achieved, in comparison to conventional HPLC methods, for instance. | |
| http://hdl.handle.net/2268/13879 |
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