Reference : Quantitative analysis of strychnine and brucine in Strychnos nux-vomica using H-1-NMR
Scientific journals : Article
Life sciences : Phytobiology (plant sciences, forestry, mycology...)
Physical, chemical, mathematical & earth Sciences : Chemistry
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/13879
Quantitative analysis of strychnine and brucine in Strychnos nux-vomica using H-1-NMR
English
Frederich, Michel mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Choi, Y. H. [> > > >]
Verpoorte, R. [> > > >]
Dec-2003
Planta Medica
Georg Thieme Verlag Kg
69
12
1169-1171
Yes (verified by ORBi)
International
0032-0943
Stuttgart
[en] A quantitative analysis using H-1-NMR (Q-NMR) has been developed for the determination of strychnine and brucine in Strychnos nux-vomica seeds and stems. The advantages of the method are that no reference alkaloids are needed for calibration curves, the quantification could be directly realized on a crude extract, strychnine and brucine could easily be distinguished, an overall profile of the preparation (including non alkaloid compounds) could be directly obtained, and a very significant time-gain could be achieved, in comparison to conventional HPLC methods, for instance.
http://hdl.handle.net/2268/13879

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