Poster (Scientific congresses and symposiums)
Automatic multiclass classification of 18FDG-PET scans for the distinction between Parkinson’s disease and atypical parkinsonian syndromes
Phillips, Christophe; Schrouff, Jessica; Luxen, André et al.
2012Organization of Human Brain Mapping
 

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Keywords :
classification; Parkinson's Syndromes; bagging
Abstract :
[en] Part of the difficulty in the early diagnosis of Parkinson’s disease (PD) is in differentiating it from atypical parkinsonian disorders (APS) that have a poorer prognosis such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). 18flurodeoxyglucose (FDG) positron emission tomography (PET) has been recommended for the early differentiation between PD and APS [1]. Here, 120 FDG PET scans (42, 31, 26 and 21 for the PD, MSA, PSP and CBS resp.) were acquired on average 3.5 years after symptoms onset (because the initial clinical features were outside the prevailing perception for PD) to look, without any a priori assumption, for cerebral FDG uptake patterns that discriminate either between the PD and APS classes, or between the four PD, MSA, PSP and CBS classes. The diagnostic used to label the scans was defined by clinical criteria on average 4.5 years after PET assessment.
Research center :
GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others
Human health sciences: Multidisciplinary, general & others
Author, co-author :
Phillips, Christophe  ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Schrouff, Jessica ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Luxen, André ;  Université de Liège - ULiège > Département de chimie (sciences) > Chimie organique de synthèse
Salmon, Eric  ;  Université de Liège - ULiège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn.
Garraux, Gaëtan  ;  Université de Liège - ULiège > Département des sciences cliniques > Neurologie
Language :
English
Title :
Automatic multiclass classification of 18FDG-PET scans for the distinction between Parkinson’s disease and atypical parkinsonian syndromes
Publication date :
10 June 2012
Event name :
Organization of Human Brain Mapping
Event place :
Beijing, China
Event date :
from 10-06-2012 to 14-06-2012
Audience :
International
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
FRIA - Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture [BE]
ULiège - Université de Liège [BE]
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since 14 January 2013

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