Article (Scientific journals)
Blood, urine, and hair kinetic analysis following an acute lead intoxication
KEUTGENS, Aurore; HO, Giang; SCHOOFS, Roland et al.
2011In Journal of Analytical Toxicology, 35 (1), p. 60-64
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Keywords :
lead; blood; urine; hair; kinetic; acute intoxication; ICP-MS; lead intoxication; hair analysis
Abstract :
[en] A case of lead exposure resulting from the accidental ingestion of a lead-containing solution is reported. Because of clinical management rapidly performed through chelation therapy by 2,3-dimercaptopropane sulfonate sodium and meso-2,3-dimercaptosuccinic acid, blood lead levels of this 51-year-old patient were moderate (412.9 μg/L) and no clinical symptoms were observed. Numerous blood and urine samples were collected for kinetic analysis of lead elimination. However, we report the first case in which hair samples were analyzed to determine the excretion level of lead after acute intoxication.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
KEUTGENS, Aurore ;  Centre Hospitalier Universitaire de Liège - CHU > Service d'hématologie biologique et immuno-hématologie
HO, Giang
SCHOOFS, Roland
KOTOLENKO, Svelana
DENOOZ, Raphael ;  Centre Hospitalier Universitaire de Liège - CHU > Toxicologie clinique
CHARLIER, Corinne  ;  Centre Hospitalier Universitaire de Liège - CHU > Toxicologie clinique
Language :
English
Title :
Blood, urine, and hair kinetic analysis following an acute lead intoxication
Publication date :
2011
Journal title :
Journal of Analytical Toxicology
ISSN :
0146-4760
eISSN :
1945-2403
Publisher :
Preston, Niles, United States - Illinois
Volume :
35
Issue :
1
Pages :
60-64
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 27 December 2010

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