No full text
Article (Scientific journals)
Corticosteroids: still at the frontline in asthma treatment?
LOUIS, Renaud; SCHLEICH, FLorence; Barnes, Peter J.
2012In Clinics in Chest Medicine, 33 (3), p. 531-41
Peer Reviewed verified by ORBi
 

Files


Full Text
No document available.
Full Text Parts
Corticosteroids_still at the frontline in asthma treatment_Louis_12_ClinChestMed.pdf
Publisher postprint (326.19 kB)
Request a copy
Corticosteroids_still at the frontline in asthma treatment_Louis_12_ClinChestMed.pdf
Author postprint (311.64 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] Inhaled corticosteroids (ICS) have led to improved asthma control and reduced asthma mortality in the Western world. ICS are effective in combating T-helper type 2-driven inflammation featuring mast cell and eosinophilic airway infiltration. Their effect on innate immunity-driven neutrophilic inflammation is poor and their ability to prevent airway remodeling and accelerated lung decline is controversial. Although ICS remain pivotal drugs in asthma management, research is needed to find drugs complementary to the combination ICS/long-acting beta2-agonist in refractory asthma and perhaps a new class of drugs as a first-line treatment in mild to moderate noneosinophilic asthma.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
LOUIS, Renaud ;  Centre Hospitalier Universitaire de Liège - CHU > Pneumologie-Allergologie
SCHLEICH, FLorence 
Barnes, Peter J.
Language :
English
Title :
Corticosteroids: still at the frontline in asthma treatment?
Publication date :
2012
Journal title :
Clinics in Chest Medicine
ISSN :
0272-5231
Publisher :
W. B. Saunders Co., United Kingdom
Volume :
33
Issue :
3
Pages :
531-41
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Copyright (c) 2012 Elsevier Inc. All rights reserved.
Available on ORBi :
since 20 November 2012

Statistics


Number of views
250 (24 by ULiège)
Number of downloads
398 (6 by ULiège)

Scopus citations®
 
36
Scopus citations®
without self-citations
26
OpenCitations
 
27

Bibliography


Similar publications



Contact ORBi