Reference : Les traitements cibles dans l'asthme: confirmations, espoirs et deceptions.
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
Les traitements cibles dans l'asthme: confirmations, espoirs et deceptions.
[en] Targeted asthma therapies: confirmations, hopes, and disappointments
SCHLEICH, FLorence mailto [> >]
LOUIS, Renaud mailto [Centre Hospitalier Universitaire de Liège - CHU > > Pneumologie-Allergologie >]
Revue Médicale de Liège
67 Spec No
Yes (verified by ORBi)
[en] Anti-Asthmatic Agents/therapeutic use ; Antibodies, Monoclonal, Humanized/therapeutic use ; Asthma/drug therapy ; Humans ; Immunoglobulin E/immunology ; Interleukins/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
[en] Asthma is a chronic inflammatory disease of the airways. The inflammatory process is driven by different pathways involving cytokines and other protein mediators. Patients with severe asthma are at high risk of severe exacerbations and death and have few therapeutic options available. Therefore, biological agents have been developed to help patients with refractory asthma by interfering with several compounds of the asthma inflammatory cascade. In addition to decreasing exacerbations, some of those treatments have a steroid sparing role and many beneficial effects in asthmatics.

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