|Reference : About the diagnosis of acute transfusion-related reaction during cardiopulmonary bypass|
|Scientific congresses and symposiums : Unpublished conference/Abstract|
|Human health sciences : Public health, health care sciences & services|
|About the diagnosis of acute transfusion-related reaction during cardiopulmonary bypass|
|[fr] Détection des réactions transfusionnelles aigues sous circulation extracorporelle|
|ERPICUM, Marie [Centre Hospitalier Universitaire de Liège - CHU > > Bloc opératoire chirurgie cardio-vasculaire >]|
|BLAFFART, Francine [Centre Hospitalier Universitaire de Liège - CHU > > Bloc opératoire chirurgie cardio-vasculaire >]|
|DEFRAIGNE, Jean [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie cardio-vasculaire >]|
|GERARD, Christiane [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie biologique et immuno hématologie >]|
|LARBUISSON, Robert [Centre Hospitalier Universitaire de Liège - CHU > > Anesthésie et réanimation >]|
|13th symposium on perfusion "Questioning the obvious in CPB practice"|
|29 septembre 2012|
|The Belgian Society of Extracorporeal Technology - BelSECT|
|[en] Cardiopulmonary bypass ; Transfusion|
|[en] Many advances have been realized in the field of blood safety during the last decade: donors’ selection, leukoreduction of packed red blood cells and platelet concentrates, genomic screening of blood-borne diseases, viral and bacterial inactivation process,... However, transfusion of blood components remains unsafe. Therefore, detecting and reporting transfusion-related complications are still essential means for both the patients’ management and the public health approach, since these measures help to adjust preventive measures to be applied in a haemovigilance purpose.
Most acute transfusion-related complications occur within minutes or hours after transfusion and require urgent medical care; delayed transfusion reactions may also develop days, even months later, implying a longer follow-up.
Transfusion of red blood cells is not infrequent during cardiac surgery with cardiopulmonary bypass. Symptoms of acute transfusion-related reactions include hypotension, diffuse bleeding, hemoglobinuria and oliguria. These symptoms are identical to those that can be observed during a complicated cardiopulmonary bypass. Consequently, identification of acute transfusion-related reactions in this particular situation is quite difficult and probably leads to an under-reporting of their occurrence.
In this paper, we explore how to track acute transfusion-related reactions during cardiopulmonary bypass. Any suspicion of such reactions must leads to investigations, in order to confirm the diagnosis. Their detection would allow to better focus their specific treatment and further their notification in a global blood safety policy.
|Service de chirurgie cardiovasculaire et thoracique|
|L'épargne sanguine à travers l'itinéraire clinique du patient opéré cardiaque|
|Researchers ; Professionals ; Students|
|File(s) associated to this reference|
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