ORBi: ERPICUM Marie - About the diagnosis of acute transfusion-related reaction during cardiopulmonary bypass

Reference : About the diagnosis of acute transfusion-related reaction during cardiopulmonary bypass


	Document type :	Scientific congresses and symposiums : Unpublished conference
	Discipline(s) :	Human health sciences : Public health, health care sciences & services
	To cite this reference:	http://hdl.handle.net/2268/133424

Title :	About the diagnosis of acute transfusion-related reaction during cardiopulmonary bypass
Language :	English
Alternative title :	[fr] Détection des réactions transfusionnelles aigues sous circulation extracorporelle
Author, co-author :	ERPICUM, Marie [Centre Hospitalier Universitaire de Liège - CHU > > Bloc opératoire chirurgie cardio-vasculaire >]
	BLAFFART, Francine [Centre Hospitalier Universitaire de Liège - CHU > > Bloc opératoire chirurgie cardio-vasculaire >]
	DEFRAIGNE, Jean [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie cardio-vasculaire >]
	GERARD, Christiane [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie biologique et immuno hématologie >]
	LARBUISSON, Robert [Centre Hospitalier Universitaire de Liège - CHU > > Anesthésie et réanimation >]
Publication date :	29-Sep-2012
On invitation :	No
Audience :	International
Event name :	13th symposium on perfusion "Questioning the obvious in CPB practice"
Event date :	29 septembre 2012
Event organizer :	The Belgian Society of Extracorporeal Technology - BelSECT
Event place (city) :	Bruxelles
Event country :	Belgique
Keywords :	[en] Cardiopulmonary bypass ; Transfusion
Abstract :	[en] Many advances have been realized in the field of blood safety during the last decade: donors’ selection, leukoreduction of packed red blood cells and platelet concentrates, genomic screening of blood-borne diseases, viral and bacterial inactivation process,... However, transfusion of blood components remains unsafe. Therefore, detecting and reporting transfusion-related complications are still essential means for both the patients’ management and the public health approach, since these measures help to adjust preventive measures to be applied in a haemovigilance purpose. Most acute transfusion-related complications occur within minutes or hours after transfusion and require urgent medical care; delayed transfusion reactions may also develop days, even months later, implying a longer follow-up. Transfusion of red blood cells is not infrequent during cardiac surgery with cardiopulmonary bypass. Symptoms of acute transfusion-related reactions include hypotension, diffuse bleeding, hemoglobinuria and oliguria. These symptoms are identical to those that can be observed during a complicated cardiopulmonary bypass. Consequently, identification of acute transfusion-related reactions in this particular situation is quite difficult and probably leads to an under-reporting of their occurrence. In this paper, we explore how to track acute transfusion-related reactions during cardiopulmonary bypass. Any suspicion of such reactions must leads to investigations, in order to confirm the diagnosis. Their detection would allow to better focus their specific treatment and further their notification in a global blood safety policy.
Research units :	Service de chirurgie cardiovasculaire et thoracique
Name of the research project :	L'épargne sanguine à travers l'itinéraire clinique du patient opéré cardiaque
Target :	Researchers ; Professionals ; Students
Permalink :	http://hdl.handle.net/2268/133424

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