[en] Introduction: Walking speed is generally considered as the best outcome measure in trials for people with multiple sclerosis (pMS). We recently designed a device based on range laser scanner capable to track feet paths of walking subjects. Our purpose was to explore gait descriptors of pMS and compare them with those of healthy volunteers (HV). Methods: Fourty-four pMS (considered as moderatly or highly disabled according to a cut-off EDSS value of 3.0) and 28 HV performed 4 walking tasks along 2 trajectories in 3 walking modes. Twenty-six gait descriptors crudely dichotomized in « efficiency» and « quality » of gait were compared in the 2 populations using unpaired t-tests. Results: (i) apart from an older age in pMS, the two populations were comparable, (ii) efficiency of gait descriptors including walking speed distinguished HV from pMS, and pMS with moderate from pMS with high disability, (iii) quality of gait descriptors were also significantly altered in pMS, including in walking tasks where their walking speed was comparable to that of HV. Conclusions: RLS technology can distinguish pMS from HV according to (i) more efficiency of gait descriptors than the sole walking speed and (ii) quality of gait descriptors, including in subjects with a « normal » walking speed.
Disciplines :
Neurology
Author, co-author :
PHAN BA, Remy ; Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Pierard, Sébastien ; Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Télécommunications
MOONEN, Gustave ; Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Van Droogenbroeck, Marc ; Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Télécommunications
Belachew, Shibeshih ; Université de Liège - ULiège > Département des sciences cliniques > Neurologie
Language :
English
Title :
Detection and Quantification of Efficiency and Quality of Gait Impairment in Multiple Sclerosis through Foot Path Analysis
Publication date :
11 October 2012
Event name :
28th Congress of the European Committee for Treatment and Research In Multiple Sclerosis
Event organizer :
European Committee for Treatment and Research In Multiple Sclerosis
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