ORBi: Tutunaru Alexandru-Cosmin - Clinical aspects of alfaxalone use in rabbits. Partial results.

Reference : Clinical aspects of alfaxalone use in rabbits. Partial results.


	Document type :	Scientific congresses and symposiums : Paper published in a book
	Discipline(s) :	Life sciences : Veterinary medicine & animal health
	To cite this reference:	http://hdl.handle.net/2268/132449

Title :	Clinical aspects of alfaxalone use in rabbits. Partial results.
Language :	English
Author, co-author :	Tutunaru, Alexandru-Cosmin [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Anesthésiologie et réanimation vétérinaires >]
	Sonea, P []
	Drion, Pierre [Université de Liège - ULg > Département des sciences biomédicales et précliniques > GIGA-R:Méth. expér.des anim. de labo et éth. en expér. anim. >]
	Duwez, Luc [Université de Liège - ULg > > GIGA-R : Services généraux de l'Université >]
	Serteyn, Didier [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux >]
	Sandersen, Charlotte [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés >]
Publication date :	15-Oct-2012
Main document title :	Proceedings BCLAS, ESLAV & ECLAM Scientific Meeting
Editor :	BCLAS, ESLAV
Pages :	20
On invitation :	No
Audience :	International
Event name :	"Sharing is Caring": New debates within the European Laboratory Animal Community
Event date :	du 15 au 16 octobre 2012
Event organizer :	BCLAS, ESLAV & ECLAM Scientific Meeting
Event place (city) :	Liège
Event country :	B
Keywords :	[en] alfaxolone ; rabbit ; anaesthesia ; respiratory status ; oxygen saturation ; apnea ; respiratory rate ; SpO2 ; End tidal Co2 ; EtCO2
Abstract :	[en] Alfaxalone, a synthetic neuroactive steroid, has been shown to induce smooth general anesthesia in wild and companion rabbits. The aim of the study was to test the effect of alfaxolone in experimental rabbits without concomitant oxygen supplementation.Respiratory status was assessed by measuring the duration of the post-induction apnea, the respiratory rate, the oxygen saturation of hemoglobin in the peripheral blood (SpO2) and the end-tidal CO2 (EtCO2) Cardiac function was assessed by monitoring heart rate using a pulse oximeter. The degree of anesthesia was monitored by evaluating ear and paw pinch reflex, as well as ocular signs such as nystagmus, exophtalmia and the loss of palpebral and corneal reflexes.
Research units :	Faculty of Veterinary Medicine Liège ; Faculty of Veterinary Medicine Bucharest ; Giga-ULg
Target :	Researchers ; Professionals ; Students
Permalink :	http://hdl.handle.net/2268/132449

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