Thomé, Jean-Pierre[Université de Liège - ULg > Département de Biologie, Ecologie et Evolution > Ecologie animale et écotoxicologie >]
23-May-2010
No
International
20th SETAC (Society of Environmental Toxicology and Chemistry)
du 23 au 27 mai 2010
[en] Putative endocrine disruptors affect rate of fertilization of sexual females by males. Preston et al. (2000) reported a decrease in fertilization rate following exposition to, notably, flutamide at 10µg/l. We observed similar effects with fenitrothion. Cross mating experiments showed that the decrease in fertilization rate is due to an impact on males exclusively. We studied the impact of anti-androgens on spermatogenesis and observed a decrease in the spermatozoa production with concentrations down to 0,5 mg L-1.We also report a detailed description of the morphology of the male reproductive apparatus in B. calyciflorus based on optic and electronic microscopy analysis and we describe the effect of anti-androgens on males and spermatogenesis in males.