Reference : La comorbidite psoriasis-syndrome metabolique, une maladie multigenique complexe.
Scientific journals : Article
Human health sciences : Dermatology
http://hdl.handle.net/2268/131779
La comorbidite psoriasis-syndrome metabolique, une maladie multigenique complexe.
French
[en] The psoriasis--metabolic syndrome comorbidity, a complex multigenic disease
Franchimont, Claudine mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
Quatresooz, Pascale mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
PIERARD, Gérald mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Scheen, André mailto [Université de Liège - ULg > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques >]
2012
Revue Médicale de Liège
67
5-6
337-40
Yes (verified by ORBi)
National
0370-629X
Belgium
[en] Psoriasis is a common chronic inflammatory dermatitis mediated by cytokines released by dendritic plasmacytoid cells in combination with Th1- and Th17-cells. This complex and multifactorial condition is commonly associated with some comorbidities. The complexity of a coordinated management of such intricated pathologies is obvious. It calls for the so-called medicine "centered around the patient" which tops off the evidence-based medicine. Vitamin D by its immunomodulatory effect on T helper cells exerts a therapeutic benefit on psoriasis and some of its comorbidities including the metabolic syndrome. A vitamin D oral treatment was proposed in order to reduce the cardiovascular risk, and the ensuing morbidity and mortality.
http://hdl.handle.net/2268/131779

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