Reference : Cardiac Transplantation Beyond 55 Years of Age
Scientific journals : Article
Human health sciences : Surgery
Human health sciences : Cardiovascular & respiratory systems
http://hdl.handle.net/2268/131621
Cardiac Transplantation Beyond 55 Years of Age
English
Defraigne, Jean-Olivier mailto [Université de Liège - ULg > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique >]
Demoulin, J. C. [Université de Liège - ULg > Département de Médecine interne > > >]
Beaujean, M. A. [Université de Liège - ULg > Département de Médecine Interne > > >]
DELBOUILLE, Marie-Hélène mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
MEURISSE, Michel mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Limet, Raymond [Université de Liège - ULg > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique]
Jul-1990
Transplant International
Springer International
3
2
59-61
Yes (verified by ORBi)
International
0934-0874
1432-2277
Heidelberg
Germany
[en] Between January 1985 and December 1988, 20 patients over the age of 55 years (extremes 56-63 years; 15 men and 5 women) underwent cardiac transplantation. The cause of cardiopathy was ischemic in 70% of the cases. The immunosuppressive regimen consisted of cyclosporin A, corticoids, and azathioprine. Rejection episodes were monitored by endomyocardial biopsies and treated by pulses of corticoids or monoclonal antibodies (OKT3). The operative mortality was 10% (n = 2). The 1-year survival rate was 70%. The 1-year incidence of infection and/or rejection episodes was 1 and 1.53 episodes/patient, respectively. One patient was successfully retransplanted after 9 months because of intractable rejection. Age beyond 55 years is no longer a contraindication to cardiac transplantation. This change in recipient selection policy should lead to parallel changes in donor selection criteria.
Researchers ; Professionals
http://hdl.handle.net/2268/131621
The original publication is available at www.springerlink.com

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