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| Reference : Consequences of total and subtotal myeloperoxidase deficiency: risk or benefit ? |
| Scientific journals : Article | |||
| Human health sciences : Hematology | |||
| http://hdl.handle.net/2268/131453 | |||
| Consequences of total and subtotal myeloperoxidase deficiency: risk or benefit ? | |
| English | |
| Kutter, D. [] | |
| Devaquet, P. [] | |
| Vanderstocken, G. [] | |
Paulus, Jean-Michel  [Université de Liège - ULg > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)] | |
| Marchal, V. [] | |
| Gothot, André [Université de Liège - ULg > > Hématologie biologique et immuno hématologie >] | |
| 2000 | |
| Acta Haematologica | |
| S. Karger | |
| 104 | |
| 1 | |
| 10-5 | |
| International | |
| 0001-5792 | |
| 1421-9662 | |
| [en] Adolescent ; Adult ; Aged ; Aged, 80 and over ; Arthritis/enzymology/etiology ; Cardiovascular Diseases/enzymology/prevention & control ; Case-Control Studies ; Chi-Square Distribution ; Child ; Child, Preschool ; Chronic Disease ; Female ; Humans ; Infection/enzymology/etiology ; Male ; Middle Aged ; Myocardial Infarction/enzymology/prevention & control ; Neoplasms/enzymology/etiology ; Peroxidase/blood/deficiency/pharmacology ; Risk Factors | |
| [en] A group of 100 totally or subtotally myeloperoxidase (MPO)-deficient individuals was compared to a reference population of 118 probands selected at random. Data for a protective effect of the deficiency against cardiovascular damage are presented. On the other hand, a significantly higher occurrence of severe infections and chronic inflammatory processes was noted among the deficient patients. An increased incidence of cancer among the MPO-deficient individuals was not demonstrated. | |
| http://hdl.handle.net/2268/131453 | |
| Copyright 2000 S. Karger AG, Basel |
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