Reference : Limited clinical utility of a self-evaluating risk assessment scale for postmenopausa...
Scientific journals : Article
Human health sciences : General & internal medicine
http://hdl.handle.net/2268/130835
Limited clinical utility of a self-evaluating risk assessment scale for postmenopausal osteoporosis: lack of predictive value of lifestyle-related factors
English
Goemaere, S [> >]
Zegels, Brigitte [Université de Liège - ULg > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé >]
Toye, K [> >]
CREMERS, Simon mailto [Centre Hospitalier Universitaire de Liège - CHU > > Cardiologie >]
Demuynck, R [> >]
Daems, M [> >]
Dobbelaere, K [> >]
Ben Sedrine, Wafa mailto [Université de Liège - ULg > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé >]
Albert, Adelin mailto [Université de Liège - ULg > Département des sciences de la santé publique > Informatique médicale et biostatistique >]
Dewé, Walthère [Université de Liège - ULg > Département des sciences cliniques > Médecine générale >]
Kaufman, JM [> >]
Reginster, Jean-Yves mailto [Université de Liège - ULg > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé >]
1999
Calcified Tissue International
Springer
65
5
354-358
Yes (verified by ORBi)
International
0171-967X
New York
NY
[en] Absorptiometry, Photon ; Age Factors ; Aged ; Aged, 80 and over ; Analysis of Variance ; Body Weight ; Bone Density/physiology ; Bone and Bones/metabolism ; Cohort Studies ; Female ; Humans ; Life Style ; Middle Aged ; Multicenter Studies as Topic ; Osteoporosis, Postmenopausal/diagnosis/prevention & control ; Questionnaires ; Regression Analysis ; Risk Factors
[en] The aim of this study was to assess the efficiency of a self-administered questionnaire to identify subjects with postmenopausal osteoporosis in the setting of first line medical care. A sample of 300 postmenopausal women completed the questionnaire based on 18 items. Bone mineral density at the lumbar spine (BMD-L), total hip (BMD-H), and femoral neck (BMD-N) was used as objective criterion for evaluation. The mean risk score was 8.2 +/- 3.21. BMD was correlated with total risk score: r = -0.32 for BMD-L, -0.36 for BMD-N, and -0.43 for BMD-H. Cutoff points for the risk score (equal likelihood points) according to a T-score threshold of -2.5 were 8.6 for BMD-L and BMD-N and 9.3 for BMD-H; specificity and sensitivity was 62% and 62%, respectively, for BMD-L, 65% and 62% for BMD-N, and 75% and 63% for BMD-H. Stepwise multiple regression analysis of the questionnaire items in relation to BMD showed higher correlation coefficients for models including individual items rather than the overall risk score. Items concerning low weight, older age, and wrist fracture after 50 years of age were always selected as significant determinants of BMD (R = 0.43-0.55). Hormonal replacement therapy was also an important determinant. Lifestyle-related items did not contribute significantly. In conclusion, the diagnostic performance of the 18-item self-administered questionnaire was poorer than a shortened questionnaire omitting lifestyle factors. The clinical utility of a questionnaire should ultimately be evaluated in the specific optic of a chosen global strategy for prevention of osteoporotic fractures.
http://hdl.handle.net/2268/130835
also: http://hdl.handle.net/2268/139810

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
Limited clinical utility of a self-evaluating risk assessment scale for postmenopausal osteoporosis lack of predictive value of lifestyle-related factors.pdfPublisher postprint126.8 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.