Reference : Is it time for implementation of tight glycaemia control by intensive insulin therapy...
Scientific journals : Other
Human health sciences : Anesthesia & intensive care
http://hdl.handle.net/2268/130718
Is it time for implementation of tight glycaemia control by intensive insulin therapy in every ICU?
English
Devos, P. [> > > >]
Preiser, Jean-Charles [Université de Liège - ULg > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine) >]
2006
Critical Care
Biomed Central
10
2
130
No
International
1364-8535
1466-609X
London
[en] Glycemic Index/drug effects/physiology ; Glycemic Index/drug effects/physiology ; Humans ; Hypoglycemic Agents/administration & dosage ; Insulin/administration & dosage ; Intensive Care Units/trends
[en] The second study on tight glycaemia control by intensive insulin therapy (IIT) confirmed in medical intensive care unit patients the decrease in hospital mortality reported by the same team in the first IIT trial in surgical patients. However, methodological concerns, the high rate of hypoglycaemia in spite of the infusion of large doses of parenteral glucose and the frequent use of steroids presently preclude considering these results as recommendations in other intensive care units, but rather argue for the need for large-scale assessment of the IIT approach by multi-centre studies to confirm the efficacy and safety of this therapeutic modality.
http://hdl.handle.net/2268/130718
10.1186/cc4871

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