Reference : Challenging regional psoriasis and ustekinumab biotherapy: impact of the patterns of ...
Scientific journals : Article
Human health sciences : Dermatology
http://hdl.handle.net/2268/130163
Challenging regional psoriasis and ustekinumab biotherapy: impact of the patterns of disease.
English
Hermanns-Lê, Trinh mailto [> >]
Berardesca, Enzo [> >]
PIERARD, Gérald mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Lesuisse, Marianne [> >]
Franchimont, Claudine mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
2012
Journal of Biomedicine & Biotechnology
2012
413767
Yes (verified by ORBi)
International
1110-7243
1110-7251
United States
[en] In some patients, psoriasis appears refractory to many treatments, particularly when the disease is confined to some specific body regions. In this respect, palmoplantar psoriasis and palmoplantar pustulosis are possibly related conditions in their immunopathomechanisms involving Il-12, IL-23, and Th17. Nail psoriasis and scalp psoriasis are two other particular psoriasis manifestations. Accordingly, ustekinumab was tested in a few of these patients. The present paper is limited to peer-reviewed case reports. Data were not supported by bioinstrumental assessments and controlled trials. Overall, they are indicative of potential efficacy. The cost-effectiveness and the risk-benefit assessments merit further investigations.
http://hdl.handle.net/2268/130163
10.1155/2012/413767

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