Article (Scientific journals)
Quantitative capabilities of four state-of-the-art SPECT-CT cameras
Seret, Alain; Nguyen, Daniel; BERNARD, Claire
2012In EJNMMI Research, 2, p. 45
Peer Reviewed verified by ORBi
 

Files


Full Text
2191-219X-2-45.pdf
Author postprint (3.87 MB)
This provisional PDF corresponds to the article as it appeared upon acceptance
Request a copy
Annexes
Additional File 1.pdf
Publisher postprint (107.7 kB)
Additional file 1 (Supplementary Figure 1)
Request a copy
Additional File 2.pdf
Publisher postprint (622.39 kB)
Additional file 2 (Preliminary study and Supplementary Figures 2 to 5)
Request a copy
Additional File 3.pdf
Publisher postprint (126.54 kB)
Additional file 3 (Supplementary Figure 6)
Request a copy
Additional File 4.pdf
Publisher postprint (153.91 kB)
Additional file 4 (Supplementary Figure 7)
Request a copy
Additional File 5.pdf
Publisher postprint (162 kB)
Additional file 5 (Supplementary Figure 8)
Request a copy
Additional File 6.pdf
Publisher postprint (124.2 kB)
Additional file 6 (Supplementary Figure 9)
Request a copy
Additional File 7.pdf
Publisher postprint (114.17 kB)
Additional file 7 (Supplementary Figure 10)
Request a copy
Additional File 8.pdf
Publisher postprint (45.27 kB)
Additional file 8 (Supplementary Figure 11)
Request a copy
Additional File 9.pdf
Publisher postprint (29.53 kB)
Additional file 9 (Supplementary Figure 12)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
SPECT; SPECT-CT; Quantification; Reconstruction; Iterative; Attenuation; Scatter; Resolution; Brightview; Discovery NM670; Infinia; Hawkeye; Symbia; Astonish; Evolution; Fash3D
Abstract :
[en] Background. Four state-of-the-art single-photon emission computed tomography-computed tomography (SPECT-CT) systems, namely Philips Brightview, General Electric Discovery NM/CT 670 and Infinia Hawkeye 4, and Siemens Symbia T6, were investigated in terms of accuracy of attenuation and scatter correction, contrast recovery for small hot and cold structures, and quantitative capabilities when using their dedicated three-dimensional iterative reconstruction with attenuation and scatter corrections and resolution recovery. Methods. The National Electrical Manufacturers Association (NEMA) NU-2 1994 phantom with cold air, water, and Teflon inserts, and a homemade contrast phantom with hot and cold rods were filled with 99mTc and scanned. The acquisition parameters were chosen to provide adequate linear and angular sampling and high count statistics. The data were reconstructed using Philips Astonish, General Electric Evolution for Bone, or Siemens Flash3D, eight subsets, and a varying number of iterations. A procedure similar to the one used in positron emission tomography (PET) allowed us to obtain the factor to convert counts per pixel into activity per unit volume. Results. Edge and oscillation artifacts were observed with all phantoms and all systems. At 30 iterations, the residual fraction in the inserts of the NEMA phantom fell below 3.5%. Contrast recovery increased with the number of iterations but became almost saturated at 24 iterations onwards. In the uniform part of the NEMA and contrast phantoms, a quantification error below 10% was achieved. Conclusions. In objects whose dimensions exceeded the SPECT spatial resolution by several times, quantification seemed to be feasible within 10% error limits. A partial volume effect correction strategy remains necessary for the smallest structures. The reconstruction artifacts nevertheless remain a handicap on the road towards accurate quantification in SPECT and should be the focus of further works in reconstruction tomography.
Research center :
GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège
Disciplines :
Radiology, nuclear medicine & imaging
Author, co-author :
Seret, Alain ;  Université de Liège - ULiège > Centre de Recherches du Cyclotron > Imagerie médicale expérimentale
Nguyen, Daniel ;  Université de Liège - ULiège > Département de physique > 2010-2011
BERNARD, Claire ;  Centre Hospitalier Universitaire de Liège - CHU > Médecine nucléaire et imagerie oncologique
Language :
English
Title :
Quantitative capabilities of four state-of-the-art SPECT-CT cameras
Publication date :
27 August 2012
Journal title :
EJNMMI Research
eISSN :
2191-219X
Publisher :
Springer, Heidelberg, Germany
Volume :
2
Pages :
45
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Open Access publication
Available on ORBi :
since 28 August 2012

Statistics


Number of views
107 (12 by ULiège)
Number of downloads
3 (3 by ULiège)

Scopus citations®
 
55
Scopus citations®
without self-citations
55
OpenCitations
 
41

Bibliography


Similar publications



Contact ORBi