Article (Scientific journals)
Tacrolimus-Based, Steroid-Free Regimens in Renal Transplantation: 3-year Follow-up of the ATLAS Trial
Krämer, Bernhard k; Klinger, Marian; Vitko, Stefan et al.
2012In Transplantation, 94 (5), p. 492-498
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Abstract :
[en] Background. Long-term use of corticosteroids is associated with considerable morbidity, including cardiovascular and metabolic adverse effects. Methods. This study evaluated the long-term efficacy and safety of two steroid-free regimens compared with a triple immunosuppressive therapy in renal transplant recipients. This was a 3-year follow-up to a 6-month, open-label, randomized, multicenter study. Results. Data from 3 years were available for 421 (93.3%) of 451 patients in the original intent-to-treat population (143 tacrolimus/basiliximab [Tac/Bas], 139 tacrolimus/mycophenolate mofetil [Tac/MMF], and 139 tacrolimus/MMF/
Disciplines :
Surgery
Author, co-author :
Krämer, Bernhard k
Klinger, Marian
Vitko, Stefan
GLYDA, Maciej
Midtvedt, Karsten
Stefoni, Sergio
Citterio, Franco
Pietruck, Frank
SQUIFFLET, Jean-Paul ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Segoloni, Giuseppe
Krüger, Bernd
Sperschneider, Heide
Banas, Bernhard
Bäckman, Lars
Weber, Markus
Carmellini, Mario
Perner, Ferenc
Claesson, Kerstin
Marcinkowski, Wojciech
Ostrowski, Marek
Senatorski, Grzegorz
Nordström, Johan
Salmela, Kaija
More authors (13 more) Less
Language :
English
Title :
Tacrolimus-Based, Steroid-Free Regimens in Renal Transplantation: 3-year Follow-up of the ATLAS Trial
Publication date :
15 September 2012
Journal title :
Transplantation
ISSN :
0041-1337
eISSN :
1534-6080
Publisher :
Lippincott Williams & Wilkins, Hagerstown, United States - Maryland
Volume :
94
Issue :
5
Pages :
492-498
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 21 August 2012

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