Reference : Pharma clinics. Comment je traite.... Certaines maladies metaboliques grace a une interv...
Scientific journals : Article
Human health sciences : Pharmacy, pharmacology & toxicology
Pharma clinics. Comment je traite.... Certaines maladies metaboliques grace a une intervention pharmacologique ciblee sur l'intestin.
[fr] Drug clinics. How I treat various metabolic diseases treated by a drug intervention that targets the intestine
Scheen, André mailto [Université de Liège - ULg > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale >]
Revue Médicale de Liège
Hopital de Baviere
Yes (verified by ORBi)
[en] Acarbose ; Anion Exchange Resins/adverse effects/therapeutic use ; Anti-Obesity Agents/adverse effects/therapeutic use ; Antilipemic Agents/adverse effects/therapeutic use ; Cholestyramine/adverse effects/therapeutic use ; Diabetes Mellitus/drug therapy ; Enzyme Inhibitors/adverse effects/therapeutic use ; Humans ; Hypercholesterolemia/drug therapy ; Hypoglycemia/drug therapy ; Hypoglycemic Agents/adverse effects/therapeutic use ; Intestine, Small/drug effects ; Lactones/adverse effects/therapeutic use ; Lipase/antagonists & inhibitors ; Metabolic Diseases/diet therapy/drug therapy ; Trisaccharides/adverse effects/therapeutic use ; alpha-Glucosidases/antagonists & inhibitors
[en] Besides the classical dietary regimen, it is possible to use specific pharmacological approaches, targeted at the intestine, in order to treat some metabolic disorders. Three approaches will be described: anionic resins for treating hypercholesterolaemia, alpha-glucosidase inhibitors for treating diabetes mellitus and reactive hypoglycaemia, and intestinal lipase inhibitors for treating obesity. All these drugs are based on original concepts, but their clinical use is often limited by the occurrence of digestive side-effects. The latter may generally be reduced by progressive and individual titration of the dosage of each drug and/or by following an appropriate diet.

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