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Article (Scientific journals)
Cardiac Transplantation in Patients Older Than 55 Years
Defraigne, Jean-Olivier; Demoulin, J.C.; VAN DAMME, Hendrik et al.
1991In Acta Chirurgica Belgica, 91 (1), p. 38-42
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Abstract :
[en] From 1985 to 1990, 27 patients older than 55 years (extremes 55-65 years; 21 men and 6 women) received a cardiac transplant. The cause of cardiopathy was ischemic in 70%. Postoperative immunosuppressive therapy consisted of Cyclosporin A, steroids, azathioprine and antilymphocytic serum. Rejection episodes were monitored by endomyocardial biopsies and treated by pulses of steroids or monoclonal antibodies (OKT3). The operative mortality is 7.4% (n = 2). The one and two year survivals are 71% and 62% respectively. The incidence of infection and/or rejection were 0.71 +/- 0.4 and 1.4 +/- 0.7 episodes/patient year. Age beyond 55 years does not contraindicate heart transplantation. This change in recipient selection policy should lead to parallel changes in donor selection criteria.
Disciplines :
Surgery
Cardiovascular & respiratory systems
Author, co-author :
Defraigne, Jean-Olivier ;  Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique
Demoulin, J.C.
VAN DAMME, Hendrik ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie cardio-vasculaire
DELBOUILLE, Marie-Hélène ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
MEURISSE, Michel ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Limet, Raymond ;  Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique
Language :
English
Title :
Cardiac Transplantation in Patients Older Than 55 Years
Publication date :
1991
Journal title :
Acta Chirurgica Belgica
ISSN :
1784-3421
eISSN :
2577-0160
Publisher :
Acta Medica Belgica, Bruxelles, Belgium
Volume :
91
Issue :
1
Pages :
38-42
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 01 August 2012

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