Reference : Chemical inhibitors: the challenge of finding the right target.
Scientific journals : Article
Human health sciences : Oncology
http://hdl.handle.net/2268/126804
Chemical inhibitors: the challenge of finding the right target.
English
Calligaris, David [Université de Liège - ULg > Département de chimie (sciences) > GIGA-R : Laboratoire de spectrométrie de masse (L.S.M.) >]
Lafitte, Daniel [> >]
May-2011
Chemistry & Biology
Current Biology
18
5
555-557
Yes (verified by ORBi)
International
1074-5521
London
United Kingdom
[en] A paper in this issue of Chemistry & Biology shows that the diaryl oxazole compound UA62784 that targets pancreatic cancer cells interacts with tubulin near the colchicine binding site (Tcherniuk et al., 2011). These findings differ from previous observations, highlighting the challenges of identifying the biological target for chemical inhibitors.
Researchers ; Professionals ; Students ; General public
http://hdl.handle.net/2268/126804
10.1016/j.chembiol.2011.05.003
http://www.sciencedirect.com/science/article/pii/S1074552111001694

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