Reference : Chitosan-based biomimetic scaffolds and methods for preparing the same
Patent : Patent
Physical, chemical, mathematical & earth Sciences : Chemistry
Engineering, computing & technology : Materials science & engineering
http://hdl.handle.net/2268/126608
Chitosan-based biomimetic scaffolds and methods for preparing the same
English
Filée, Patrick [ > > ]
Freichels, Astrid [University of Liège (ULg) > > > >]
Jérôme, Christine mailto [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Aqil, Abdelhafid [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Colige, Alain mailto [University of Liège (ULg) > > > >]
Tchemtchoua Tateu, Victor mailto [University of Liège (ULg) > > > >]
14-Dec-2011
2010-06-04
European Patent office
EP 2394670
EP20100164959 20100604
A
Europe
University of Liège (ULg)
A61L15/28; A61L15/42
A61L15/28; A61L15/42E; A61L15/64; A61L27/20; A61L27/48; A61L27/56; A61L27/58; A61L27/60
-
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR BA ME RS
[en] biomaterial ; scaffold ; chitosan ; nanofiber ; electrospinning
[en] The invention concerns chitosan-based biomimetic scaffolds and methods for modulating their intrinsic properties such as rigidity, elasticity, resistance to mechanical stress, porosity, biodegradation and absorbance of exudates. Therefore, the present invention relates to a layered chitosan-based scaffold wherein said layered scaffold comprises at least two fused layers, wherein at least one layer consists of a chitosan nanofiber scaffold membrane and at least one of the other layers of a porous chitosan scaffold support layer. Moreover, the present invention provides a layered chitosan-based scaffold characterized by (i) a good adhesion between the porous and nanofiber layers, (ii) a tuneable porosity of the nanofiber layer by tuning the distance between the nanofibers, (iii) a stable nanofibers and porous morphology even when immersed in water or other solvents and a process for the preparation of such layered chitosan-based scaffold.Finally, the present invention provides the use of the layered electrospun chitosan-based scaffold of the invention or the layered electrospun chitosan-based scaffold produced by the process of the invention as a wound dressing, in tissue engineering or for biomedical applications.
Center for Education and Research on Macromolecules (CERM)
Researchers
http://hdl.handle.net/2268/126608

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