Abraham, N.G., Levere, R.D., Freedman, M.L., Effect of age on rat liver heme and drug metabolism (1985) Exp. Gerontol., 20, pp. 277-284
Agarwal, S.K., Khatri, S., Anuradha, S., Singh, N.P., Baveja, U., Tumour necrosis factor-alpha and interleukin-2 in pus aspirate and blood in patients with amoebic liver abscess (1999) J. Assoc. Physicians India, 47, pp. 1065-1067
Agrawal, A., Tay, J., Ton, S., Agrawal, S., Gupta, S., Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA (2009) J. Immunol., 182, pp. 1138-1145
Beers, C., Burich, A., Kleijmeer, M.J., Griffith, J.M., Wong, P., Rudensky, A.Y., Cathepsin S controls MHC class II-mediated antigen presentation by epithelial cells in vivo (2005) J. Immunol., 174, pp. 1205-1212
Borlon, C., Vankoningsloo, S., Godard, P., Debacq-Chainiaux, F., Toussaint, O., Identification of p53-dependent genes potentially involved in UVB-mediated premature senescence of human skin fibroblasts using siRNA technology (2008) Mech. Ageing Dev., 129, pp. 109-119
Borlon, C., Weemaels, G., Godard, P., Debacq-Chainiaux, F., Lemaire, P., Deroanne, C., Toussaint, O., Expression profiling of senescent-associated genes in human dermis from young and old donors. Proof-of-concept study (2008) Biogerontology, 9, pp. 197-208
Boucher, N., Dufeu-Duchesne, T., Vicaut, E., Farge, D., Effros, R.B., Schachter, F., CD28 expression in T cell aging and human longevity (1998) Exp. Gerontol., 33, pp. 267-282
Calabrese, V., Cornelius, C., Mancuso, C., Pennisi, G., Calafato, S., Bellia, F., Bates, T.E., Rizzarelli, E., Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (2008) Neurochem. Res., 33, pp. 2444-2471
Chapman, H.A., Endosomal proteases in antigen presentation (2006) Curr. Opin. Immunol., 18, pp. 78-84
Chowdhury, I., Mo, Y., Gao, L., Kazi, A., Fisher, A.B., Feinstein, S.I., Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element (2009) Free Radic. Biol. Med., 46, pp. 146-153
Dan, S., Shirakawa, M., Mukai, Y., Yoshida, Y., Yamazaki, K., Kawaguchi, T., Matsuura, M., Yamori, T., Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines (2003) Cancer Sci., 94, pp. 1074-1082
de Longueville, F., Surry, D., Meneses-Lorente, G., Bertholet, V., Talbot, V., Evrard, S., Chandelier, N., Rasson, J.P., Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray (2002) Biochem. Pharmacol., 64, pp. 137-149
de Magalhaes, J.P., Chainiaux, F., de Longueville, F., Mainfroid, V., Migeot, V., Marcq, L., Remacle, J., Toussaint, O., Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase (2004) Exp. Gerontol., 39, pp. 1379-1389
Debacq-Chainiaux, F., Borlon, C., Pascal, T., Royer, V., Eliaers, F., Ninane, N., Carrard, G., Boffe, S., Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway (2005) J. Cell Sci., 118, pp. 743-758
Debacq-Chainiaux, F., Pascal, T., Boilan, E., Bastin, C., Bauwens, E., Toussaint, O., Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts (2008) Free Radic. Biol. Med., 44, pp. 1817-1832
Deussing, J., Roth, W., Saftig, P., Peters, C., Ploegh, H.L., Villadangos, J.A., Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation (1998) Proc. Natl. Acad. Sci. USA, 95, pp. 4516-4521
Fagiolo, U., Cossarizza, A., Scala, E., Fanales-Belasio, E., Ortolani, C., Cozzi, E., Monti, D., Paganelli, R., Increased cytokine production in mononuclear cells of healthy elderly people (1993) Eur. J. Immunol., 23, pp. 2375-2378
Faria, A.M., de Moraes, S.M., de Freitas, L.H., Speziali, E., Soares, T.F., Figueiredo-Neves, S.P., Vitelli-Avelar, D.M., Soares, E.B., Variation rhythms of lymphocyte subsets during healthy aging (2008) Neuroimmunomodulation, 15, pp. 365-379
Farooqui, T., Farooqui, A.A., Aging: an important factor for the pathogenesis of neurodegenerative diseases (2009) Mech. Ageing Dev., 130, pp. 203-215
Flynn, A., Proud, C.G., The role of eIF4 in cell proliferation (1996) Cancer Surv., 27, pp. 293-310
Franceschi, C., Valensin, S., Fagnoni, F., Barbi, C., Bonafe, M., Biomarkers of immunosenescence within an evolutionary perspective: the challenge of heterogeneity and the role of antigenic load (1999) Exp. Gerontol., 34, pp. 911-921
Fulop Jr., T., Gagne, D., Goulet, A.C., Desgeorges, S., Lacombe, G., Arcand, M., Dupuis, G., Age-related impairment of p56lck and ZAP-70 activities in human T lymphocytes activated through the TcR/CD3 complex (1999) Exp. Gerontol., 34, pp. 197-216
Galvin, J.E., Ginsberg, S.D., Expression profiling in the aging brain: a perspective (2005) Ageing Res. Rev., 4, pp. 529-547
Gillet, J.P., Efferth, T., Steinbach, D., Hamels, J., de Longueville, F., Bertholet, V., Remacle, J., Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes (2004) Cancer Res., 64, pp. 8987-8993
Gupta, S., Hopner, S., Rupp, B., Gunther, S., Dickhaut, K., Agarwal, N., Cardoso, M.C., Jung, G., Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules (2008) PLoS ONE, 3, pp. e1814
Gupta, S., Kim, C., Yel, L., Gollapudi, S., A role of fas-associated death domain (FADD) in increased apoptosis in aged humans (2004) J. Clin. Immunol., 24, pp. 24-29
Hewitt, E.W., Treumann, A., Morrice, N., Tatnell, P.J., Kay, J., Watts, C., Natural processing sites for human cathepsin E and cathepsin D in tetanus toxin: implications for T cell epitope generation (1997) J. Immunol., 159, pp. 4693-4699
Hori, R., Kashiba, M., Toma, T., Yachie, A., Goda, N., Makino, N., Soejima, A., Suematsu, M., Gene transfection of H25A mutant heme oxygenase-1 protects cells against hydroperoxide-induced cytotoxicity (2002) J. Biol. Chem., 277, pp. 10712-10718
Huppert, F.A., Solomou, W., O'Connor, S., Morgan, K., Sussams, P., Brayne, C., Aging and lymphocyte subpopulations: whole-blood analysis of immune markers in a large population sample of healthy elderly individuals (1998) Exp. Gerontol., 33, pp. 593-600
Kang, M.J., Kim, H.J., Kim, H.K., Lee, J.Y., Kim, D.H., Jung, K.J., Kim, K.W., Chung, H.Y., The effect of age and calorie restriction on HIF-1-responsive genes in aged liver (2005) Biogerontology, 6, pp. 27-37
Lee, P.J., Alam, J., Wiegand, G.W., Choi, A.M., Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia (1996) Proc. Natl. Acad. Sci. USA, 93, pp. 10393-10398
Leung, T.K., Rajendran, M.Y., Monfries, C., Hall, C., Lim, L., The human heat-shock protein family. Expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA (1990) Biochem. J., 267, pp. 125-132
Lim, W., Ma, W., Gee, K., Aucoin, S., Nandan, D., Diaz-Mitoma, F., Kozlowski, M., Kumar, A., Distinct role of p38 and c-Jun N-terminal kinases in IL-10-dependent and IL-10-independent regulation of the costimulatory molecule B7.2 in lipopolysaccharide-stimulated human monocytic cells (2002) J. Immunol., 168, pp. 1759-1769
Lindsten, T., Lee, K.P., Harris, E.S., Petryniak, B., Craighead, N., Reynolds, P.J., Lombard, D.B., Gray, G.S., Characterization of CTLA-4 structure and expression on human T cells (1993) J. Immunol., 151, pp. 3489-3499
Lio, D., Candore, G., Cigna, D., D'Anna, C., Di Lorenzo, G., Giordano, C., Lucania, G., Caruso, C., In vitro T cell activation in elderly individuals: failure in CD69 and CD71 expression (1996) Mech. Ageing Dev., 89, pp. 51-58
Maubach, G., Lim, M.C., Kumar, S., Zhuo, L., Expression and upregulation of cathepsin S and other early molecules required for antigen presentation in activated hepatic stellate cells upon IFN-gamma treatment (2007) Biochim. Biophys. Acta, 1773, pp. 219-231
Nel, A.E., T-cell activation through the antigen receptor. Part 1: Signaling components, signaling pathways, and signal integration at the T-cell antigen receptor synapse (2002) J. Allergy Clin. Immunol., 109, pp. 758-770
Pascal, T., Debacq-Chainiaux, F., Boilan, E., Ninane, N., Raes, M., Toussaint, O., Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide and ethanol (2007) Biogerontology, 8, pp. 409-422
Pascal, T., Debacq-Chainiaux, F., Chretien, A., Bastin, C., Dabee, A.F., Bertholet, V., Remacle, J., Toussaint, O., Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays (2005) FEBS Lett., 579, pp. 3651-3659
Patterson, T.A., Lobenhofer, E.K., Fulmer-Smentek, S.B., Collins, P.J., Chu, T.M., Bao, W., Fang, H., Tikhonova, I.R., Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project (2006) Nat. Biotechnol., 24, pp. 1140-1150
Pawelec, G., Effros, R.B., Caruso, C., Remarque, E., Barnett, Y., Solana, R., T cells and aging (update February 1999) (1999) Front. Biosci., 4, pp. D216-D269
Plackett, T.P., Boehmer, E.D., Faunce, D.E., Kovacs, E.J., Aging and innate immune cells (2004) J. Leukoc. Biol., 76, pp. 291-299
Riley, J.L., June, C.H., The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation (2005) Blood, 105, pp. 13-21
Salmond, R.J., Filby, A., Qureshi, I., Caserta, S., Zamoyska, R., T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance (2009) Immunol. Rev., 228, pp. 9-22
Salomon, B., Bluestone, J.A., Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation (2001) Annu Rev Immunol, 19, pp. 225-252
Shen, L., Rock, K.L., Cellular protein is the source of cross-priming antigen in vivo (2004) Proc. Natl. Acad. Sci. USA, 101, pp. 3035-3040
Shi, L., Reid, L.H., Jones, W.D., Shippy, R., Warrington, J.A., Baker, S.C., Collins, P.J., Lee, K.Y., The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements (2006) Nat. Biotechnol., 24, pp. 1151-1161
Smyth, G.K., Yang, Y.H., Speed, T., Statistical issues in cDNA microarray data analysis (2003) Methods Mol Biol, 224, pp. 111-136
Soti, C., Csermely, P., Molecular chaperones and the aging process (2000) Biogerontology, 1, pp. 225-233
Thoman, M.L., Weigle, W.O., The cellular and subcellular bases of immunosenescence (1989) Adv Immunol, 46, pp. 221-261
Thompson, C.B., Lindsten, T., Ledbetter, J.A., Kunkel, S.L., Young, H.A., Emerson, S.G., Leiden, J.M., June, C.H., CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines (1989) Proc. Natl. Acad. Sci. USA, 86, pp. 1333-1337
Vallejo, A.N., CD28 extinction in human T cells: altered functions and the program of T-cell senescence (2005) Immunol. Rev., 205, pp. 158-169
van Duin, D., Allore, H.G., Mohanty, S., Ginter, S., Newman, F.K., Belshe, R.B., Medzhitov, R., Shaw, A.C., Prevaccine determination of the expression of costimulatory B7 molecules in activated monocytes predicts influenza vaccine responses in young and older adults (2007) J. Infect. Dis., 195, pp. 1590-1597
Vankoningsloo, S., De Pauw, A., Houbion, A., Tejerina, S., Demazy, C., de Longueville, F., Bertholet, V., Holvoet, P., CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes (2006) J. Cell Sci., 119, pp. 1266-1282
Vasto, S., Candore, G., Balistreri, C.R., Caruso, M., Colonna-Romano, G., Grimaldi, M.P., Listi, F., Caruso, C., Inflammatory networks in ageing, age-related diseases and longevity (2007) Mech. Ageing Dev., 128, pp. 83-91
Villadangos, J.A., Riese, R.J., Peters, C., Chapman, H.A., Ploegh, H.L., Degradation of mouse invariant chain: roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism (1997) J. Exp. Med., 186, pp. 549-560
Waghray, A., Keppler, D., Sloane, B.F., Schuger, L., Chen, Y.Q., Analysis of a truncated form of cathepsin H in human prostate tumor cells (2002) J. Biol. Chem., 277, pp. 11533-11538
Xiao, C., Yang, B.F., Asadi, N., Beguinot, F., Hao, C., Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells (2002) J. Biol. Chem., 277, pp. 25020-25025
Xiao, C.W., Ash, K., Tsang, B.K., Nuclear factor-kappaB-mediated X-linked inhibitor of apoptosis protein expression prevents rat granulosa cells from tumor necrosis factor alpha-induced apoptosis (2001) Endocrinology, 142, pp. 557-563
Zdanov, S., Debacq-Chainiaux, F., Remacle, J., Toussaint, O., Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts (2006) FEBS Lett., 580, pp. 6455-6463