Article (Scientific journals)
18fdg-Pet for the Assessment of Primary Head and Neck Tumors: Clinical, Computed Tomography, and Histopathological Correlation in 38 Patients
Paulus, Patrick; Sambon, A.; Vivegnis, Danielle et al.
1998In Laryngoscope, 108 (10), p. 1578-83
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Keywords :
FDG-PET; Head and neck cancer; lymph node metastasis; recurrent disease
Abstract :
[en] OBJECTIVES: To evaluate the clinical usefulness of FDG-PET (fluoro-2-deoxy-glucose-positron emission tomography) in the detection of lymph node involvement and recurrences in patients with head and neck cancer. STUDY DESIGN: Retrospective review of 38 patients with biopsy-proven head and neck cancers who underwent clinical, computed tomography (CT), and FDG-PET examinations. Twenty-five patients were studied prior to therapy and 13 patients were evaluated for disease recurrence. METHODS: All patients were operated and clinical data, CT, and FDG-PET results were correlated with histopathological findings. RESULTS: All primary tumors in 25 patients were detected, with the exception of one small superficial localization of the epiglottis. Histopathological examination showed lymph node involvement in 10 patients; PET detected lymph node involvement in five. FDG-PET found one case of nodal disease not identified by clinical and CT examination. With so few cases, this could be anecdotal. Five false-negative results (microscopic lymph node involvement) and two false positives were noted. Twelve of 13 patients with recurrent disease were correctly identified with FDG-PET. FDG-PET was the only imaging technique to identify local recurrence in two patients and lymph node involvement in two others. One false-positive result occurred in a patient with a foreign body granuloma. CONCLUSIONS: FDG-PET is a useful diagnostic modality for the detection of recurrent tumors and, in selected cases, precise lymph node involvement. The best way to further investigate the utility of clinical FDG-PET is in the follow-up of treated patients.
Disciplines :
Radiology, nuclear medicine & imaging
Oncology
Author, co-author :
Paulus, Patrick
Sambon, A.
Vivegnis, Danielle
Hustinx, Roland  ;  Université de Liège - ULiège > Département des sciences cliniques > Médecine nucléaire
Moreau, Pierre ;  Centre Hospitalier Universitaire de Liège - CHU > O.R.L.
Collignon, Jacques ;  Centre Hospitalier Universitaire de Liège - CHU > Imagerie médicale
Deneufbourg, Jean-Marie  ;  Université de Liège - ULiège > Département des sciences cliniques > Radiothérapie
Rigo, Pierre ;  Université de Liège - ULiège > Département des sciences de la motricité > Pathologie générale et médecine nucléaire
Language :
English
Title :
18fdg-Pet for the Assessment of Primary Head and Neck Tumors: Clinical, Computed Tomography, and Histopathological Correlation in 38 Patients
Publication date :
October 1998
Journal title :
Laryngoscope
ISSN :
0023-852X
eISSN :
1531-4995
Publisher :
Wiley-Blackwell, United States - Pennsylvania
Volume :
108
Issue :
10
Pages :
1578-83
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 22 January 2010

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