ORBi: Le Dinh Hieu - Liège experience in donation after cardiac death liver transplantation: 2003-2011

Reference : Liège experience in donation after cardiac death liver transplantation: 2003-2011


	Document type :	Scientific congresses and symposiums : Paper published in a journal
	Discipline(s) :	Human health sciences : Surgery Human health sciences : Gastroenterology & hepatology
	To cite this reference:	http://hdl.handle.net/2268/126042

Title :	Liège experience in donation after cardiac death liver transplantation: 2003-2011
Language :	English
Author, co-author :	Le Dinh, Hieu [Université de Liège - ULg > > > Doct. sc. médicales (Bologne)]
	DELWAIDE, Jean [Centre Hospitalier Universitaire de Liège - CHU > > Gastro-Entérologie-Hépatologie >]
	MONARD, Josée [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
	DE ROOVER, Arnaud [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
	HONORE, Pierre [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
	SQUIFFLET, Jean-Paul [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
	Meurisse, Michel [Université de Liège - ULg > Département des sciences cliniques > Chirurgicale abdominale >]
	DETRY, Olivier [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Publication date :	May-2012
Journal title :	Acta Chirurgica Belgica
Publisher :	Acta Medica Belgica
Volume :	112
Issue/season :	3
Pages :	68.FP11.
Peer reviewed :	Yes (verified by ORBi)
On invitation :	No
Audience :	National
ISSN :	0001-5458
City :	Bruxelles
Country :	Belgique
Event name :	Thirteenth Belgian Surgical Week
Event date :	du 9 au 12 mai 2012
Event organizer :	Royal Belgian Society for Surgery
Event place (city) :	Spa
Event country :	Belgium
Keywords :	[en] nhbd ; liver ; results
Abstract :	[en] Objectives: Results of DCD-LT at the University Hospital of Liège were evaluated from 2003 to 2011. Methods: Medical records of 56 DCD liver recipients were retrospectively reviewed with regard to patient and graft survivals and biliary complications. Mean follow-up was 26.4 months. Mean donor age was 56.3±14.5 years (25 - 83). Donor causes of death were due to anoxia (51.8%), stroke (32.1%) and head trauma (14.3%). Mean WIT, CIT and suture time were 20.5±7.1min (10 – 39), 265.6±85.1min (105 – 576), and 40.8±7.8 min (25 – 61), respectively. 95% of liver grafts were locally shared. HTK was the most commonly used perfusion solution (86%). Mean recipient age was 56.6±10.5 years (29 – 73). Indications for LT included ESLD (53.6%) and HCC (46.6%). Mean MELD score at transplant was 15.6±6.1points (6 – 40). Results: No primary non-function grafts. Mean peak serum AST and bilirubin levels were 2520±3621UI/L and 50.2±49.2mg/L, respectively. Eight patients (14.3%) developed biliary complications. No intra-hepatic bile duct strictures or re-transplantation. Global patient and graft survival was 92.6% at 3 months, 92.6% at 1 year, 73.8% at 3 years and 60% at 5 years. Death-censored patient and graft survival at the corresponding time points was 92.6%, 92.6%, 87.7% and 87.7%. Thirteen liver grafts were lost during follow-up exclusively due to recipient deaths. The rate of HCC recurrence was 33.3%. Conclusions: Controlled DCD donors are a valuable source of transplantable liver grafts. Primary results are encouraging and apparently as good as those from brain-dead donation LT essentially due to short WIT and CIT.
Target :	Researchers ; Professionals ; Students ; General public
Permalink :	http://hdl.handle.net/2268/126042

File(s) associated to this reference

Fulltext file(s):

	File	Commentary	Version	Size	Access
Open access	ledinh 1607.pdf		Publisher postprint	34.21 kB	View/Open

All documents in ORBi are protected by a user license.

Dspace v1.5