Patent (Patents)
DETECTION OF SPECIFIC NITRATED MARKERS
Reginster, Jean-Yves; Deberg, Michelle; Henrotin, Yves et al.
2004
 

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Abstract :
[en] Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
Disciplines :
Rheumatology
Inventor :
Reginster, Jean-Yves  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Deberg, Michelle
Henrotin, Yves  ;  Université de Liège - ULiège > Département des sciences de la motricité > Unité de recherche sur l'os et le cartillage (U.R.O.C.)
Christgau, Stephan
Language :
English
Title (54) :
DETECTION OF SPECIFIC NITRATED MARKERS
Publication date (43-45) :
22 December 2004
Filing date (22) :
12 March 2003
Patent/publication number (10-11) :
EP1488240 A2
Patent status (13) :
A
Priority number (30) :
20020000381 DK 13.03.2002
International classification (IPC) (51) :
C07K16/18; G01N33/53; G01N33/537; G01N33/543; G01N33/564; G01N33/68; (IPC1-7): C07K16/00; C07K16/18; C12N5/00; G01N33/564; G01N33/68
European classification (ECLA) (52) :
C07K16/18; G01N33/564; G01N33/68A; G01N33/68R; G01N33/68V; G01N33/68V2
Applicant (71) :
Université de Liège Avenue Pré-Aily, 4 4031 Angleur / BE
Publication organism (19) :
Office Europeen des brevets
Available on ORBi :
since 23 June 2012

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