Reference : METHOD FOR MONITORING COLLAGEN TYPE II DEGRADATION IN CARTILAGE
Patent : Patent
Human health sciences : Rheumatology
http://hdl.handle.net/2268/125966
METHOD FOR MONITORING COLLAGEN TYPE II DEGRADATION IN CARTILAGE
English
Reginster, Jean-Yves[Université de Liège - ULg > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé >]
Université de Liège Avenue Pré-Aily, 4 4031 Angleur / BE
C07K16/18; G01N33/68; (IPC1-7): G01N33/68
C07K16/18; G01N33/68R
AT , BE , BG , CH , CY , CZ , DE , DK , EE , ES , FI , FR , GB , GR , HU , IE , IT , LI , LU , MC , NL , PT , RO , SE , SI , SK , TR
AT , BE , BG , CH , CY , CZ , DE , DK , EE , ES , FI , FR , GB , GR , HU , IE , IT , LI , LU , MC , NL , PT , RO , SE , SI , SK , TR
[en] A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals ultizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG, located in the helical region of collagen type II.