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| Reference : Glucotoxicite et lipotoxicite, deux complices impliques dans le cercle vicieux du diabet... |
| Scientific journals : Article | |||
| Human health sciences : Endocrinology, metabolism & nutrition | |||
| http://hdl.handle.net/2268/12561 | |||
| Glucotoxicite et lipotoxicite, deux complices impliques dans le cercle vicieux du diabete de type 2. | |
| French | |
| [fr] Glucotoxicity and lipotoxicity, two implicated accomplices in the vicious circle of type 2 diabetes | |
Scheen, André  [Université de Liège - ULg > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale >] | |
| Paquot, Nicolas [Centre Hospitalier Universitaire de Liège - CHU > > Diabétologie,nutrition, maladies métaboliques >] | |
| Lefebvre, Pierre [Centre Hospitalier Universitaire de Liège - CHU > > Diabétologie,nutrition, maladies métaboliques >] | |
| 1999 | |
| Revue Médicale de Liège | |
| Hopital de Baviere | |
| 54 | |
| 6 | |
| 535-8 | |
| 0370-629X | |
| Liège | |
| Belgique | |
| [en] Diabetes Mellitus, Type 2/metabolism/prevention & control/therapy ; Disease Progression ; Glucose/metabolism ; Humans ; Insulin/pharmacology/physiology ; Insulin Resistance/physiology ; Lipid Metabolism | |
| [en] Type 2 diabetes mellitus is a dynamic disease whose natural history is characterized by a progressive aggravation leading to a progressively severe hyperglycaemia, which generally requires a more complex therapy as time progresses. Such an evolution results from a vicious circle where both glucotoxicity and lipotoxicity contribute to reduce insulin secretion and the action of insulin on cell glucose metabolism. These new concepts are able to modify the strategies of prevention and treatment of type 2 diabetes. | |
| http://hdl.handle.net/2268/12561 |
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