Article (Scientific journals)
Vitamin D tweets light to genes in multiple sclerosis
LOMMERS, Emilie; Lecrompe, Laurence; Moonen, Gustave et al.
2012In Revue Médicale de Liège, 67 (5-6), p. 359-365
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Keywords :
Vitamin D; Multiple sclerosis
Abstract :
[en] The relationship between sunlight exposure and the incidence of multiple sclerosis and the understanding of immunomodulatory effects of vitamin D triggered, in recent years, a broad range of investigations. Immunological studies performed in vitro and in vivo have demonstrated how tolerogenic vitamin D can be. Epidemiological studies confirmed an increased incidence of multiple sclerosis in vitamin D deficient subjects and signs of increased disease activity in such MS patients. Although small-scale observational studies have suggested a beneficial impact of vitamin D supplementation on the incidence and severity of multiple sclerosis, large scale clinical trials remain warranted to confirm these preliminary results.
Disciplines :
Neurology
Author, co-author :
LOMMERS, Emilie  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Lecrompe, Laurence ;  Université de Liège - ULiège > 3e an. méd.
Moonen, Gustave  ;  Université de Liège - ULiège > Département des sciences cliniques > Neurologie
PHAN BA, Remy ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Belachew, Shibeshih ;  Université de Liège - ULiège > Département des sciences cliniques > Neurologie
Language :
French
Title :
Vitamin D tweets light to genes in multiple sclerosis
Alternative titles :
[fr] La Vitamine D connecte la lumière aux gènes dans la sclérose en plaques
Publication date :
2012
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
Volume :
67
Issue :
5-6
Pages :
359-365
Peer reviewed :
Peer reviewed
Available on ORBi :
since 14 June 2012

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