Article (Scientific journals)
SAPS 3 admission score: an external validation in a general intensive care population
Ledoux, Didier; Canivet, Jean-Luc; Preiser, Jean-Charles et al.
2008In Intensive Care Medicine
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Keywords :
intensive care; severity of illness model; outcome research
Abstract :
[en] OBJECTIVES: To validate the SAPS 3 admission score in an independent general intensive care case mix and to compare its performances with the APACHE II and the SAPS II scores. DESIGN: Cohort observational study. SETTING: A 26-bed general ICU from a Tertiary University Hospital. PATIENTS AND PARTICIPANTS: Eight hundred and fifty-one consecutive patients admitted to the ICU over an 8-month period. Of these patients, 49 were readmissions, leaving 802 patients for further analysis. INTERVENTION: None. MEASUREMENTS AND RESULTS: APACHE II, SAPS II and SAPS 3 variables were prospectively collected; scores and their derived probability of death were calculated according to their original manuscript description. The discriminative power was assessed using the area under the ROC curve (AUROC) and calibration was verified with the Hosmer-Lemeshow goodness-of-fit test. The AUROC of the APACHE II model (AUROC = 0.823) was significantly lower than those of the SAPS II (AUROC = 0.850) and SAPS 3 models (AUROC = 0.854) (P = 0.038). The calibration of the APACHE II model (P = 0.037) and of the SAPS 3 global model (P = 0.035) appeared unsatisfactory. On the contrary, both SAPS II model and SAPS 3 model customised for Central and Western Europe had a good calibration. However, in our study case mix, SAPS II model tended to overestimate the probability of death. CONCLUSION: In this study, the SAPS 3 admission score and its prediction model customised for Central and Western Europe was more discriminative and better calibrated than APACHE II, but it was not significantly better than the SAPS II.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Ledoux, Didier  ;  Université de Liège - ULiège > Soins intensifs
Canivet, Jean-Luc ;  Université de Liège - ULiège > Soins intensifs
Preiser, Jean-Charles ;  Université de Liège - ULiège > Soins intensifs
Lefrancq, Joëlle ;  Université de Liège - ULiège > Soins intensifs
Damas, Pierre ;  Université de Liège - ULiège > Soins intensifs
Language :
English
Title :
SAPS 3 admission score: an external validation in a general intensive care population
Publication date :
01 July 2008
Journal title :
Intensive Care Medicine
ISSN :
0342-4642
eISSN :
1432-1238
Publisher :
Springer Verlag, New York, United States - New York
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 22 March 2010

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