Article (Scientific journals)
Le medicament du mois. Valdecoxib (Bextra)
Scheen, André; Malaise, Michel
2004In Revue Médicale de Liège, 59 (4), p. 251-254
Peer reviewed
 

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Keywords :
Anti-Inflammatory Agents, Non-Steroidal/administration & dosage/therapeutic use; Arthritis, Rheumatoid/drug therapy; Cyclooxygenase Inhibitors/administration & dosage/therapeutic use; Dysmenorrhea/drug therapy; Enzyme Inhibitors/administration & dosage/therapeutic use; Female; Humans; Infusions, Intravenous; Injections, Intramuscular; Isoxazoles/administration & dosage/therapeutic use; Osteoarthritis/drug therapy; Pain, Postoperative/drug therapy; Prodrugs; Sulfonamides/administration & dosage/therapeutic use
Abstract :
[en] Valdecoxib (Bextra tablets of 10 mg and 20 mg) is a new non steroidal antiinflammatory drug (NSAID) that selectively inhibits COX-2 isoform of cyclo-oxygenase. It is indicated for the symptomatic treatment of osteoarthritis or rheumatoid arthritis (10 to 20 mg once a day) and for the treatment of primary dysmenorrhea (40 mg once a day). Valdecoxib is as efficacious as conventional non-COX-2 selective NSAIDs, but offers the advantage of a much better gastrointestinal tolerance. Valdecoxib has a prodrug that can be administered intravenously or intramuscularly (parecoxib, Dynastat) and has been developed for the short-term treatment of postsurgical pain.
Disciplines :
Rheumatology
Pharmacy, pharmacology & toxicology
Author, co-author :
Scheen, André  ;  Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale
Malaise, Michel ;  Centre Hospitalier Universitaire de Liège - CHU > Rhumatologie
Language :
French
Title :
Le medicament du mois. Valdecoxib (Bextra)
Alternative titles :
[en] Valdecoxib (Bextra)
Publication date :
2004
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
Volume :
59
Issue :
4
Pages :
251-254
Peer reviewed :
Peer reviewed
Additional URL :
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