Reference : Factor XIII a-positive dermal dendrocytes and shear wave propagation in human skin.
Scientific journals : Article
Human health sciences : Dermatology
http://hdl.handle.net/2268/12501
Factor XIII a-positive dermal dendrocytes and shear wave propagation in human skin.
English
Hermanns-Le, Trinh mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Uhoda, I. [Centre Hospitalier Universitaire de Liège - CHU > > > > Dermatopathologie > >]
Pierard, Claudine mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Pierard, Gérald mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
2002
European Journal of Clinical Investigation
Blackwell Publishing
32
11
847-51
Yes (verified by ORBi)
0014-2972
1365-2362
Oxford
United Kingdom
[en] Adult ; Case-Control Studies ; Cell Count ; Dermis/cytology/metabolism/physiopathology ; Factor XIIIa/metabolism ; Gastroplasty ; Humans ; Logistic Models ; Male ; Obesity/metabolism/physiopathology/surgery ; Shear Strength ; Tensile Strength
[en] BACKGROUND: The in vivo interdependence between the phenotypic characteristics of dermal cells and the strain imposed on the tissue has not been studied thoroughly in humans. In particular the mechanical force modulation of Factor XIII a expression in dermal dendrocytes (DD) remains unknown. MATERIALS AND METHODS: The present study compares the numerical density of Factor XIII a-positive DD and the in vivo shear wave velocity in the skin. The investigation was performed in 20 men of normal weight and 20 obese men before and after entering a slimming process. RESULTS: Excess cutaneous fat places the skin under increased intrinsic tension. The resonance running time measurement (RRTM) and the DD density were significantly reduced in overweight individuals. After a short-term but intense slimming process, the same individuals showed a trend to normalization of these two parameters without, however, reaching significance. Pooling all data yielded a significant logarithmic correlation between RRTM values and densities in Factor XIII a-positive DD. CONCLUSION: Factor XIII a expression in human DD may be partially regulated by the intrinsic resting tensions in the skin.
http://hdl.handle.net/2268/12501

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