Reference : Effects of Nimesulide and Indometacin on Cox-1 and Cox-2: A Comparative Study
Scientific journals : Article
Human health sciences : Rheumatology
http://hdl.handle.net/2268/125006
Effects of Nimesulide and Indometacin on Cox-1 and Cox-2: A Comparative Study
English
de Leval, X. [> > > >]
Dogné, Jean-Michel [Université de Liège - ULg > Département de pharmacie > Département de pharmacie >]
Neven, P. [> > > >]
Labasse, Alain [Centre Hospitalier Universitaire de Liège - CHU > > Médecine de l'appareil locomoteur >]
Delarge, J. [> > > >]
Reginster, Jean-Yves mailto [Université de Liège - ULg > Département des sciences de la santé publique > Epidémiologie et santé publique >]
Henrotin, Yves mailto [Université de Liège - ULg > > Unité de recherche sur l'os et le cartillage (U.R.O.C.) >]
1999
Journal de Pharmacie de Belgique
54
3
89-90
Yes (verified by ORBi)
International
0047-2166
[en] Evidence of the existence of two forms of cyclooxygenases and the clinical relevance of COX-2 inhibition led to the development of COX-2 selective NSAIDs. In order to evaluate this selectivity, we have developed and validated an enzymatic method. The precision and reproducibility of the assay were determined and COX-2 selectivity examined using nimesulide and indometacin.
http://hdl.handle.net/2268/125006

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