Reference : Risk assessment for furan contamination through the food chain in Belgian children
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/123152
Risk assessment for furan contamination through the food chain in Belgian children
English
Scholl, Georges mailto [Université de Liège - ULg > > Center for Analytical Research and Technology (CART) >]
Huybrechts, Inge mailto [Ghent University > Department of Public Health > > >]
Humblet, Marie-France mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Epidémiologie et analyse des risques appl. aux sc. vétér. >]
Scippo, Marie-Louise mailto [Université de Liège - ULg > Département de sciences des denrées alimentaires > Analyse des denrées alimentaires >]
De Pauw, Edwin mailto [Université de Liège - ULg > Département de chimie (sciences) > GIGA-R : Laboratoire de spectrométrie de masse (L.S.M.) >]
Eppe, Gauthier mailto [Université de Liège - ULg > > Chimie analytique inorganique >]
Saegerman, Claude mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Epidémiologie et analyse des risques appl. aux sc. vétér. >]
Aug-2012
Food Additives & Contaminants
Taylor & Francis Ltd
29
8
1219-1229
Yes (verified by ORBi)
International
0265-203X
1464-5122
[en] furan ; children ; risk assessment ; food chain ; belgium ; deterministic approach ; probabilistic approach ; Monte Carlo Simulation ; margin of exposure
[en] Young, old, pregnant and immuno-compromised persons are of great concern for risk assessors as they represent the sub-populations most at risk. The present paper focuses on risk assessment linked to furan exposure in children. Only the Belgian population was considered because individual contamination and consumption data that are required for accurate risk assessment were available for Belgian children only. Two risk assessment approaches, so called deterministic and probabilistic, were applied and their results were compared for the estimation of the daily intake. A significant difference between the average Estimated Daily Intake (EDI) was underlined between the deterministic (419 ng * (kgb.w. * day)-1) and the probabilistic (583 ng * (kgb.w. * day)-1) approaches, which results from the mathematical treatment of the null consumption and contamination data. The risk was characterized by two ways: (1) the classical approach by comparison of the EDI to a reference dose (RfDchronic-oral) and (2) the most recent approach, namely the Margin of Exposure (MoE) approach. Both reached similar conclusions: the risk level is not of a major concern, but is neither negligible. In the first approach, only 2.7% or 6.6% (respectively in the deterministic and in the probabilistic way) of the studied population presented an EDI above the RfDchronic-oral. In the second approach, the percentage of children displaying a MoE above 10,000 and below 100 is 3% - 0% and 20% - 0.01% in the deterministic and probabilistic modes respectively. In addition, children were compared to adults and significant differences between the contamination patterns were highlighted. Whilst major contamination was linked to coffee consumption in adults (55%), no item predominantly contributed to the contamination in children. The most important were soups (19%), dairy products (17%), pasta and rice (11%), fruit and potatoes (9% each).
Centre Interfacultaire d'Analyse des Résidus en Traces - CART
Belgian Federal Public Service of Health, Food Chain Safety and Environment
http://hdl.handle.net/2268/123152
also: http://hdl.handle.net/2268/132502
10.1080/19440049.2012.686456
http://www.tandfonline.com/doi/abs/10.1080/19440049.2012.686456

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
19440049.2012.pdfPublisher postprint614.2 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.