Article (Scientific journals)
Risk assessment for furan contamination through the food chain in Belgian children
Scholl, Georges; Huybrechts, Inge; Humblet, Marie-France et al.
2012In Food Additives and Contaminants, 29 (8), p. 1219-1229
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Keywords :
furan; children; risk assessment; food chain; belgium; deterministic approach; probabilistic approach; Monte Carlo Simulation; margin of exposure
Abstract :
[en] Young, old, pregnant and immuno-compromised persons are of great concern for risk assessors as they represent the sub-populations most at risk. The present paper focuses on risk assessment linked to furan exposure in children. Only the Belgian population was considered because individual contamination and consumption data that are required for accurate risk assessment were available for Belgian children only. Two risk assessment approaches, so called deterministic and probabilistic, were applied and their results were compared for the estimation of the daily intake. A significant difference between the average Estimated Daily Intake (EDI) was underlined between the deterministic (419 ng * (kgb.w. * day)-1) and the probabilistic (583 ng * (kgb.w. * day)-1) approaches, which results from the mathematical treatment of the null consumption and contamination data. The risk was characterized by two ways: (1) the classical approach by comparison of the EDI to a reference dose (RfDchronic-oral) and (2) the most recent approach, namely the Margin of Exposure (MoE) approach. Both reached similar conclusions: the risk level is not of a major concern, but is neither negligible. In the first approach, only 2.7% or 6.6% (respectively in the deterministic and in the probabilistic way) of the studied population presented an EDI above the RfDchronic-oral. In the second approach, the percentage of children displaying a MoE above 10,000 and below 100 is 3% - 0% and 20% - 0.01% in the deterministic and probabilistic modes respectively. In addition, children were compared to adults and significant differences between the contamination patterns were highlighted. Whilst major contamination was linked to coffee consumption in adults (55%), no item predominantly contributed to the contamination in children. The most important were soups (19%), dairy products (17%), pasta and rice (11%), fruit and potatoes (9% each).
Research center :
CART - Centre Interfacultaire d'Analyse des Résidus en Traces - ULiège
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Scholl, Georges ;  Université de Liège - ULiège > Center for Analytical Research and Technology (CART)
Huybrechts, Inge;  Ghent University > Department of Public Health
Humblet, Marie-France ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Epidémiologie et analyse des risques appl. aux sc. vétér.
Scippo, Marie-Louise  ;  Université de Liège - ULiège > Département de sciences des denrées alimentaires > Analyse des denrées alimentaires
De Pauw, Edwin  ;  Université de Liège - ULiège > Département de chimie (sciences) > GIGA-R : Laboratoire de spectrométrie de masse (L.S.M.)
Eppe, Gauthier  ;  Université de Liège - ULiège > Chimie analytique inorganique
Saegerman, Claude  ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Epidémiologie et analyse des risques appl. aux sc. vétér.
Language :
English
Title :
Risk assessment for furan contamination through the food chain in Belgian children
Publication date :
August 2012
Journal title :
Food Additives and Contaminants
ISSN :
0265-203X
eISSN :
1464-5122
Publisher :
Taylor & Francis Ltd
Volume :
29
Issue :
8
Pages :
1219-1229
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
FPS Health Federal Public Service Health, Food Chain Safety and Environment [BE]
Available on ORBi :
since 22 May 2012

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