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Evidence-based medicine. Apport des essais cliniques controles.
Scheen, André
2000In Revue Médicale de Liège, 55 (4), p. 216-9
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Keywords :
Attitude of Health Personnel; Controlled Clinical Trials as Topic; Drug Therapy; Evidence-Based Medicine; Humans; Practice Guidelines as Topic; Research Design
Abstract :
[en] Controlled clinical trials are the support of Evidence-Based Medicine. In most instances, only them can indeed provide the demonstration of both the efficacy and safety of a pharmacological treatment, based upon rigorous scientific experimental observations avoiding potential bias due to subjective interpretation. In order to be able to extrapolate conclusions of drug trials to clinical practice and to positively influence physician's attitudes, "explanatory" trials, which aim at proving the intrinsic activity of the molecule, should be completed by "pragmatic" trials, which aim at demonstrating the clinical utility of the drug.
Disciplines :
General & internal medicine
Author, co-author :
Scheen, André  ;  Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale
Language :
French
Title :
Evidence-based medicine. Apport des essais cliniques controles.
Alternative titles :
[fr] Evidence-based medicine. Input of controlled clinical trials
Publication date :
2000
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Hopital de Baviere, Liège, Belgium
Volume :
55
Issue :
4
Pages :
216-9
Peer reviewed :
Peer reviewed
Available on ORBi :
since 06 May 2009

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