ORBi: Kaux Jean-François - Platelet-rich plasma to treat jumper’s knee: preliminary results

Reference : Platelet-rich plasma to treat jumper’s knee: preliminary results


	Document type :	Scientific congresses and symposiums : Paper published in a book
	Discipline(s) :	Human health sciences : Orthopedics, rehabilitation & sports medicine
	To cite this reference:	http://hdl.handle.net/2268/122524

Title :	Platelet-rich plasma to treat jumper’s knee: preliminary results
Language :	English
Author, co-author :	Kaux, Jean-François [Université de Liège - ULg > Département des sciences de la motricité > Département des sciences de la motricité >]
	CROISIER, Jean-Louis [Centre Hospitalier Universitaire de Liège - CHU > > Médecine de l'appareil locomoteur >]
	SIMONI, Paolo [Centre Hospitalier Universitaire de Liège - CHU > > Imagerie de l'appareil locomoteur >]
	Lonneux, Vincent [ > > ]
	Lapraille, Stuart [ > > ]
	Brabant, Gautier [ > > ]
	Noël, David [ > > ]
	Rodriguez de la Cruz, Carlos [Université de Liège - ULg > Département des sciences de la motricité > Physiologie humaine et physiologie de l'effort physique >]
	DANIEL, Christophe [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie appareil locomoteur >]
	COLLETTE, Julien [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
	Gothot, André [Université de Liège - ULg > Département des sciences cliniques > Département des sciences cliniques >]
	LE GOFF, Caroline [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
	Crielaard, Jean-Michel [Université de Liège - ULg > Département des sciences de la motricité > Evaluation et entraînement des aptitudes physiques >]
Publication date :	Apr-2012
Main document title :	Biomedica 2012
Pages :	181
Peer reviewed :	Yes
Audience :	International
Event name :	Biomedica 2012 - The European Life Sciences Summit
Event date :	18-19 April 2012
Event place (city) :	Liège
Event country :	Belgique
Abstract :	[en] Introduction: Tendinopathies, especially jumper’s knee, often remain rebel to conservative treatments. Several experimental studies have shown the healing properties of platelet and their growth factors. Researches have specifically demonstrated the platelets action as mediator and/or enhancer of tissue healing. The aim of our study was to investigate the effect of 1 injection of PRP in patients suffering from chronic jumper’s knee. Our protocol was approved by Ethic Committee of University and University Hospital of Liège. Methods: Patients performed imaging (US and MRI) and functional assessments, and a clinical examination using an algometer, before treatment and 6 weeks after PRP treatment. They were also invited to answer to questionnaire relative to pain and functional status. PRP was obtained from autologous blood using an apheresis system (COM.TEC, Fresenius). The injection of 6mL of PRP was realised without local anaesthesia into the proximal insertion of the patellar tendon. A 48h rest-time was recommended after infiltration. Afterwards, a submaximal eccentric reeducation was initiated 1 week after infiltration 3 times a week during 5 weeks. In case of pain, anti-inflammatory drugs were prohibited and patient were encouraged to take class I or II painbrakers. Results: At this time, 10 patients with jumper’s knee were included in our study. Pre-injection tests revealed pain of the upper part of the patellar tendon just below the patella, associated with loss of function. Imaging exams confirmed diagnosis. Six weeks post-injection, the clinical status was improved in all patients, with a significant decrease of algo-functional scores. The pain reported during functional assessments was decreased (in particular for the eccentric actions), yet no significant improvement of physical performances was observed. We found no significant differences between imaging exams before and 6 weeks after PRP injection. Conclusion: One in situ injection of PRP clinically improved patients with jumper’s knee 6 weeks after treatment. All the 10 patients reported a decrease of pain during day-life and through physical activities. However nor functional performances neither imaging were improved.
Permalink :	http://hdl.handle.net/2268/122524

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