ORBi: Mc Entee Kathleen - Doppler Echocardiographic Study of Left and Right Ventricular Function During Dobutamine Stress Testing in Conscious Healthy Dogs

Reference : Doppler Echocardiographic Study of Left and Right Ventricular Function During Dobutamine...


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Veterinary medicine & animal health
	To cite this reference:	http://hdl.handle.net/2268/121218

Title :	Doppler Echocardiographic Study of Left and Right Ventricular Function During Dobutamine Stress Testing in Conscious Healthy Dogs
Language :	English
Author, co-author :	Mc Entee, Kathleen [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Sémiologie et clinique médicale des petits animaux >]
	Clercx, Cécile [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Pathologie médicale des petits animaux >]
	Amory, Hélène [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Médecine interne des équidés >]
	Geudvert, Claudine [Centre Hospitalier Universitaire de Liège - CHU > > Médecine de l'appareil locomoteur >]
	Dardenne, J. J. [> > > >]
	Soyeur, Daniel [Université de Liège - ULg > Département des sciences cliniques > Cardiologie]
	Henroteaux, Marc [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés >]
Publication date :	Jul-1999
Journal title :	American Journal of Veterinary Research
Publisher :	American Veterinary Medical Association
Volume :	60
Issue/season :	7
Pages :	865-71
Peer reviewed :	Yes (verified by ORBi)
Audience :	International
ISSN :	0002-9645
Abstract :	[en] OBJECTIVE: To evaluate left and right ventricular filling and ejection performances by use of Doppler echocardiography in healthy, conscious dogs submitted to dobutamine stress testing. ANIMALS: 10 unsedated, healthy adult Beagles. PROCEDURE: Doppler echocardiography was performed during cardiac stress testing on each dog twice at 24-hour intervals. Dobutamine was infused in 10 micrograms/kg of body weight/min incremental dosages, from 12.5 to 42.5 micrograms/kg/min. Duration of each step was 15 minutes. Doppler measurements were recorded at baseline and at each stage of dobutamine infusion, whereas aortic diameter was measured at baseline and at peak dosage by use of two-dimensional echocardiography. RESULTS: Dobutamine infusion induced a significant increase in velocity time integrals and in peak flow velocities at the aortic, pulmonic, mitral, and tricuspid valves. Acceleration time-to-deceleration time ratio at the aortic wave also was increased significantly. On the other hand, ejection time, acceleration time, and deceleration time at the aortic and pulmonic valves and peak flow velocity of the E wave-to-peak flow velocity of the A wave ratio at the mitral and tricuspid valves decreased significantly during the test. The acceleration time-to-deceleration time ratio at the pulmonic wave was unchanged. A significant, progressive increase in cardiac index also was observed during dobutamine infusion, with a maximal increase of 104% from baseline. This was mediated initially by an increase in stroke index and, at higher dosages, by an increase in heart rate. CONCLUSIONS AND CLINICAL RELEVANCE: Doppler echocardiography performed during dobutamine stress testing may be a reliable method of assessing myocardial function in dogs with cardiovascular disease.
Target :	Researchers ; Professionals
Permalink :	http://hdl.handle.net/2268/121218

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