ORBi: Vreuls Christelle - Biomolecule-based antibacterial coating on a stainless steel surface: multilayer film build-up optimization and stability study.

Reference : Biomolecule-based antibacterial coating on a stainless steel surface: multilayer film bu...


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Biochemistry, biophysics & molecular biology
	To cite this reference:	http://hdl.handle.net/2268/120873

Title :	Biomolecule-based antibacterial coating on a stainless steel surface: multilayer film build-up optimization and stability study.
Language :	English
Author, co-author :	Vreuls, Christelle [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
	Zocchi, Germaine [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
	Vandegaart, Hélène [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
	Faure, Emilie [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
	Detrembleur, Christophe [Université de Liège - ULg > > Centre d'études et de rech. sur les macromolécules (CERM) >]
	Duwez, Anne-Sophie [Université de Liège - ULg > Département de chimie (sciences) > Nano-chimie et systèmes moléculaires >]
	Martial, Joseph [Université de Liège - ULg > Département des sciences de la vie > Département des sciences de la vie >]
	Van de Weerdt, Cécile [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
Publication date :	28-Apr-2012
Journal title :	Biofouling
Publisher :	Taylor & Francis
Volume :	28
Issue/season :	4
Pages :	395-404
Peer reviewed :	Yes (verified by ORBi)
ISSN :	0892-7014
e-ISSN :	1029-2454
City :	London
Country :	United Kingdom
Keywords :	[en] Polyelectrolyte multilayer films ; polyelectrolyte complexes ; antibacterial peptides
Abstract :	[en] The goal of this paper was to establish the durability profile of antibacterial multilayer thin films under storage and usage conditions. Thin films were built on stainless steel (SS) by means of a layer-by-layer process alternating a negatively charged polyelectrolyte, polyacrylic acid, with a cationic antibacterial peptide, nisin. SS coupons coated with the antibacterial film were challenged under environmental and usage conditions likely to be encountered in real-world applications. The change in antibacterial activity elicited by the challenge was used as an indicator of multilayer film resistance. Antibacterial SS samples could be stored for several weeks at 4°C in ambient air and antibacterial films were resistant to dipping and mild wiping in water and neutral detergent. The multilayer coating showed some weaknesses, however, that need to be addressed.
Research units :	Giga-Systems Biology and Chemical Biology
Funders :	RW
Name of the research project :	Biocoat
Permalink :	http://hdl.handle.net/2268/120873

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