ORBi: To Hong - Endometrial thickness in different cut-off points for predicting abnormal endometrium in Vietnamese women with postmenopausal bleeding

Reference : Endometrial thickness in different cut-off points for predicting abnormal endometrium in...


	Document type :	Scientific congresses and symposiums : Paper published in a journal
	Discipline(s) :	Human health sciences : Reproductive medicine (gynecology, andrology, obstetrics)
	To cite this reference:	http://hdl.handle.net/2268/118701

Title :	Endometrial thickness in different cut-off points for predicting abnormal endometrium in Vietnamese women with postmenopausal bleeding
Language :	English
Author, co-author :	To, Hong [Université de Liège - ULg > > > Doct. sc. médicales (Bologne)]
Publication date :	26-Aug-2011
Journal title :	Ultrasound in Medicine & Biology
Publisher :	Elsevier Science
Volume :	37
Issue/season :	8S
Special issue title :	Special issue: Abstract of the 13th congress of Ultrasound in Medicine and Biology
Pages :	s118
On invitation :	Yes
Audience :	International
ISSN :	0301-5629
Event name :	The 13th world congress of Ultrasound in Medicine and Biology
Event date :	du 26 au 29 août 2011
Event organizer :	World Federation for Ultrasound in Medicine and Biology (WFUMB)
Event place (city) :	Vienna
Event country :	Austria
Keywords :	[en] Endometrial thickness ; Postmenopausal bleeding ; Transvaginal sonography
Abstract :	[en] Purpose: The aim of this study is to find the suitable cutoff point of endometrial thickness (ET) for predicting abnormal endometrium in Vietnamese women with postmenopausal bleeding (PMB). Material & Methods: A prospective study was carried out during 2 years. 308 women, who did not use any hormone therapy, were suffered from PMB. All of them were measured ET by transvaginal sonography before an endometrial biopsy. Dilation and curettage (D&C) was indicated in women with ET ≥ 3 mm to diagnose an abnormal endometrium (hyperplasia atypia or cancer). We compared the sensitivity and false-negative rate at each 1-mm interval cutoff point of ET for detecting these histopathologies. Results: 292 women gave their consent to perform an endometrial biopsy (D&C). Their mean age was 59.4 ± 9.3 years. The median time of amenorrhea was 5 years (range 2-13 years); 12.67% (95%CI 9.10-17.04) of cases were diagnosed an abnormal ET in which the mean of endometrial thickness found was 4.0±1.7 mm (95% CI 3.8-11.8). In comparison to seven cutoff points, the ET at 4 mm showed the highest detection rate of abnormal endometrium in women with PMB (95% of sensitivity for 4% false-negative rate) Conclusion: The ET at 4 mm is the most suitable cutoff point for predicting an abnormal endometrium in Vietnamese women with PMB.
Permalink :	http://hdl.handle.net/2268/118701

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