Reference : Tolerance to the Foeto-Placental 'Graft': Ten Ways to Support a Child for Nine Months

	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Immunology & infectious disease
	To cite this reference:	http://hdl.handle.net/2268/1167

Title :	Tolerance to the Foeto-Placental 'Graft': Ten Ways to Support a Child for Nine Months
Language :	English
Author, co-author :	Thellin, Olivier [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie humaine >]
	Coumans, Bernard [Université de Liège - ULg > > CNCM/ Centre fac. de rech. en neurobiologie cell. et moléc. >]
	Zorzi, Willy [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie humaine >]
	Igout, Ahmed [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
	Heinen, Ernst [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie humaine >]
Publication date :	Dec-2000
Journal title :	Current Opinion in Immunology
Publisher :	elsevier
Volume :	12
Issue/season :	6
Pages :	731-7
Audience :	International
ISSN :	0952-7915
Keywords :	[en] feotus ; allograft ; th1/th/2
Abstract :	[en] Tolerance to the foetal 'allograft' has been extensively studied in the past few years, providing interesting new insights. In addition to a potential role for HLA-G, which has been widely discussed, there are hypotheses suggesting roles for several other molecules or cells: leukemia inhibitory factor and its receptor; indoleamine 2. 3-dioxygenase; the Th1/Th2 balance; suppressor macrophages; hormones such as progesterone or the placental growth hormone; CD95 and its ligand; and, as recently proposed, annexin II. Tolerance of the foetal allograft is probably the consequence of a wide panel of mechanisms that may or may not be pregnancy-specific, that are of major or secondary importance and that may be interconnected.
Target :	Researchers ; Professionals ; Students
Permalink :	http://hdl.handle.net/2268/1167

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