Patterns of aluminum hydroxychloride deposition onto the skin.

[en] BACKGROUND: Aluminum hydroxychloride (AlCl(3) ) is an antiperspirant. AIM: To revisit the AlCl(3) deposition in vivo and in vitro on glass slides and stratum corneum (SC) harvested by cyanoacrylate skin surface strippings (CSSS). METHODS: Transepidermal water loss (TEWL) was assessed following application of 5% AlCl(3) on the forearms. The AlCl(3) -coated skin, glass slides and CSSS were observed using two ultraviolet light-emitting CCD cameras in order to record changes in specular reflectance related to AlCl(3) deposition. In addition, the corneoxenometry bioassay was performed in order to predict AlCl(3) irritation. RESULTS: AlCl(3) deposited on glass slides looked as linear threads and rings of similar sizes. AlCl(3) deposits on skin were almost restricted inside the microrelief lines and as annular deposits at their crossings where acrosyringia are opening. After daily AlCl(3) applications, deposits extended on the CSSS plateaus. At rest in absence of sweating, TEWL was decreased following AlCl(3) applications. During physical exercise, the TEWL increase was limited on the AlCl(3) areas. CSSS appeared unreactive to AlCl(3) at the corneoxenometry bioassay. CONCLUSION: The similar aspect of AlCl(3) deposits on human SC and on glass slides suggested a physical property of AlCl(3) . Repetitive applications of AlCl(3) increased both the deposit area and the barrier function.

Disciplines :

Dermatology

Author, co-author :

Mayeux, Geraldine; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Xhauflaire-Uhoda, Emmanuelle; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

PIERARD, Gérald ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Language :

English

Title :

Patterns of aluminum hydroxychloride deposition onto the skin.

Publication date :

2012

Journal title :

Skin Research and Technology

ISSN :

0909-752X

eISSN :

1600-0846

Publisher :

Blackwell Publishing, Oxford, United Kingdom

Volume :

Issue :

Pages :

64-9

Peer reviewed :

Peer Reviewed verified by ORBi

Commentary :

Available on ORBi :

since 29 March 2012

Statistics

Number of views

59 (1 by ULiège)

Number of downloads

0 (0 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

Bibliography

Marks R. The stratum corneum barrier: the final frontier. J Nutr 2004; 134: 2017S-2021S.
Uhoda E, Piérard-Franchimont C, Debatisse B, Wang X, Piérard GE.Repair kinetics of stratum corneum under repeated insults. Exog Dermatol 2004; 3: 7-11.
Pinnagoda J, Tupker RA, Agner T, Serup J.Guidelines for transepidermal water loos (TEWL) measurement. Contact Dermat 1990; 22: 164-178.
Rogiers V EEMCO group. EEMCO guidance for the assessment of transepidermal water loss in cosmetic sciences. Skin Pharmacol Appl Skin Physiol 2001; 4: 117-128.
Elkeeb R, Hui X, Chan H, Tian L, Maibach HI.Correlation of transepidermal water loss with skin barrier properties in vitro: comparison of three evaporimeters. Skin Res Technol 2010; 16: 9-15.
Quatrale RP. The mechanism of antiperspirant action. Cosmet Toilet 1985; 100: 23-26.
Uhoda E, Piérard-Franchimont C, Petit L, Piérard GE.Skin weathering and ashiness in black Africans. Eur J Dermatol 2003; 13: 574-478.
Uhoda E, Petit L, Piérard-Franchimont C, Piérard GE.Ultraviolet light-enhanced visualization of cutaneous signs of carotene and vitamin A dietary deficiency. Acta Clin Bel 2004; 59: 97-101.
Quatresooz P, Piérard GE.The Visioscan-driven ULEV and SELS methods. In: Barel AO, Paye M, Maibach HI, eds. Handbook of cosmetic science and technology, 3rd edn. New York, USA: Informa Healthcare, 2009: 283-290.
Szepetiuk G, Piérard-Franchimont C, Quatresooz Pet al. How I explore ... skin by photodiagnosis using skin fluorescence and its functional imaging. Rev Med Liège 2010; 65: 521-526.
Szepetiuk G, Piérard S, Piérard-Franchimont Cet al. Recent trends in specular light reflectance beyond clinical fluorescence diagnosis. Eur J Dermatol 2011; (in press).
Goffin V, Henry F, Piérard-Franchimont C, Piérard GE.Penetration enhancers assessed by corneoxenometry. Skin Pharmacol Appl Skin Physiol 2000; 13: 280-284.
Piérard-Franchimont C, Arrese-Estrada J, Quatresooz P, Piérard GE.Cyanoacrylate skin surface strippings. In: Farage M, Miller KW, Maibach HI, eds. Textbook of aging skin Chapter 39 Berlin: Springer Verlag, 2010: 393-399.
Rougier A, Lotte C, Corcuff P, Maibach HI.Relationship between skin permeability and corneocyte size according to anatomic site, age and sex in man. J Soc Cosmet Chem 1988; 39: 15-26.
Potts RO, Francoeur ML.The influence of stratum corneum morphology on water permeability. J Invest Dermatol 1991; 96: 495-499.
Ya-Xian Z, Suetake T, Tagami H.Number of cell layers of the stratum corneum in normal skin - relationship to the anatomical location on the body, age, sex and physical parameters. Arch Dermatol Res 1999; 291: 555-559.
Quatrale RP, Coble DW, Stoner KLet al. The mechanism of antiperspirant action on aluminium salts II. Historical observations of human eccrine sweat glands inhibited by aluminium chlorohydrate. J Soc Cosmet Chem 1981; 32: 107-136.
Quatrale RP, Coble DW, Stoner KLet al. Mechanism of antiperspirant action on aluminium salts III. Historical observations of human sweat glands inhibited by aluminium zirconium chlorohydrate glycine complex. J Soc Cosmet Chem 1981; 32: 195-221.
Laden K, Felger CB.Antiperspirants and deodorants. New York: Marcel Dekker, 1988.
Piérard GE, Piérard-Franchimont C, Kligman A.Kinetics of sebum excretion evaluated by the Sebutape-Chromameter technique. Skin Pharmacol 1993; 6: 38-44.
Uhoda E, Piérard-Franchimont C, Petit L, Piérard GE.The conundrum of skin pores in dermocosmetology. Dermatology 2005; 210: 3-7.