Article (Scientific journals)
Introduction a l'analyse spectrale des reseaux microvasculaires du melanome cutane primitif.
Quatresooz, Pascale; PIERARD, Gérald; FRANCHIMONT, Claudine et al.
2010In Pathologie Biologie, 60, p. 149-153
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Abstract :
[en] Cutaneous malignant melanoma represents one of the most dramatic skin cancers because its incidence is steadily growing in White populations. Of note, its metastatic risk and mortality dramatically increase when the primary neoplasm reaches about one millimeter thick. It is believed that angiogenesis and lymphangiogenesis associated with cutaneous melanoma potentially influence the neoplastic progression of the primary tumor and its metastases. In some instances, both the intratumoral and peritumoral microvasculature are correlated to booming of the tumoral growth fraction. In addition, the vascular network serves as a migration path for the intravascular and perivascular neoplastic spread. Hence, the quantification of the microvasculature might help establishing a prognostic factor of evolution. Among the available methods, spectral analysis of immunohistochemical sections highlighting vessels helps defining the microvasculature distribution. The benefit of using spectral analysis is discussed and the modalities of application of this analytical method are scrutinized.
Disciplines :
Dermatology
Author, co-author :
Quatresooz, Pascale  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
PIERARD, Gérald ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
FRANCHIMONT, Claudine ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Humbert, Philippe;  Hôpital Saint Jacques, Besançon, France > Dermatologie
Pierard, Sébastien ;  Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Télécommunications
Language :
French
Title :
Introduction a l'analyse spectrale des reseaux microvasculaires du melanome cutane primitif.
Alternative titles :
Spectral analysis of the microvasculature of primary cutaneous melanoma.
Publication date :
2010
Journal title :
Pathologie Biologie
ISSN :
0369-8114
eISSN :
1768-3114
Publisher :
Elsevier, Paris, France
Volume :
60
Pages :
149-153
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
Available on ORBi :
since 29 March 2012

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