[en] Acyclovir/therapeutic use ; Antiviral Agents/therapeutic use ; Herpes Labialis/drug therapy/pathology ; Humans ; Hydrogen-Ion Concentration ; Lipoproteins/therapeutic use ; Recurrence ; Skin Physiological Phenomena
[en] Recurrent herpes labialis is a frequent disorder. It occurs following the reactivation of the Herpesvirus (HSV1 and more rarely HSV2) inside the Gasser ganglion. Treatment and prevention of recurrent labial herpes are targeted by specific antiviral agents. Spectacular benefits obtained in the immunocompromised patients are less convincing in otherwise healthy subjects. Other prospective ways of therapy are under consideration, including lipopeptides and physical means aiming at modifying the cutaneous pH.