Article (Scientific journals)
Reversal of oxalosis cardiomyopathy after combined liver and kidney transplantation
Detry, Olivier; Honore, Pierre; De Roover, Arnaud et al.
2002In Transplant International, 15 (1), p. 50-52
Peer Reviewed verified by ORBi
 

Files


Full Text
Oxalurie.pdf
Publisher postprint (115.1 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
hyperoxaluria; oxalosis; cardiomyopathy; liver transplantation; kidney transplantation; case report
Abstract :
[en] Few data have been published on the course of oxalosis cardiomyopathy after combined liver and kidney transplantation in hyperoxaluria patients with myocardial involvement. We report the case of a primary hyperoxaluria type I patient with renal failure who developed end-stage cardiomyopathy. Left venticulography showed severe diffuse hypokinesia and left ventricular ejection fraction was calculated at 12%. Endomyocardial biopsy demonstrated platelike calcium oxalate crystals within the myocardium and the connective tissue, and mild perivascular fibrosis. The patient was first considered for combined liver-heart-kidney transplantation, but as his cardiac function improved slightly with an intensive dialysis program, combined liver and kidney transplantation was performed. Normal cardiac function was demonstrated at 1-year follow-up, and comparative endomyocardial biopsy showed regression of the myocardial oxalate deposits. This case adds stronger clinical, hemodynamic, and histopathological evidence that severe oxalosis cardiomyopathy may be reversed after combined liver and kidney transplantation.
Disciplines :
Surgery
Endocrinology, metabolism & nutrition
Anesthesia & intensive care
Gastroenterology & hepatology
General & internal medicine
Author, co-author :
Detry, Olivier  ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Honore, Pierre ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
De Roover, Arnaud ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Trimeche, Mounir
Demoulin, Jean-Claude
Beaujean, Marianne
Moonen, Martial
Godon, Jean-Pierre
Boniver, Jacques ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Jacquet, Nicolas
Meurisse, Michel ;  Université de Liège - ULiège > Département des sciences cliniques > Chirurgicale abdominale
Language :
English
Title :
Reversal of oxalosis cardiomyopathy after combined liver and kidney transplantation
Publication date :
January 2002
Journal title :
Transplant International
ISSN :
0934-0874
eISSN :
1432-2277
Publisher :
Springer-Verlag, New York, United States - New York
Volume :
15
Issue :
1
Pages :
50-52
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 26 November 2008

Statistics


Number of views
146 (14 by ULiège)
Number of downloads
418 (8 by ULiège)

Scopus citations®
 
33
Scopus citations®
without self-citations
33
OpenCitations
 
27

Bibliography


Similar publications



Contact ORBi