Reference : Reversal of oxalosis cardiomyopathy after combined liver and kidney transplantation
Scientific journals : Article
Human health sciences : Endocrinology, metabolism & nutrition
Human health sciences : Anesthesia & intensive care
Human health sciences : Gastroenterology & hepatology
Human health sciences : General & internal medicine
Human health sciences : Surgery
http://hdl.handle.net/2268/1151
Reversal of oxalosis cardiomyopathy after combined liver and kidney transplantation
English
Detry, Olivier mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Honore, Pierre mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
De Roover, Arnaud mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Trimeche, Mounir [> > > >]
Demoulin, Jean-Claude [> >]
Beaujean, Marianne [> > > >]
Moonen, Martial [> >]
Godon, Jean-Pierre [> >]
Boniver, Jacques mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques]
Jacquet, Nicolas [> >]
Meurisse, Michel mailto [Université de Liège - ULg > Département des sciences cliniques > Chirurgicale abdominale]
Jan-2002
Transplant International
Springer-Verlag
15
1
50-52
Yes (verified by ORBi)
International
0934-0874
New York
[en] hyperoxaluria ; oxalosis ; cardiomyopathy ; liver transplantation ; kidney transplantation ; case report
[en] Few data have been published on the course of oxalosis cardiomyopathy after combined liver and kidney transplantation in hyperoxaluria patients with myocardial involvement. We report the case of a primary hyperoxaluria type I patient with renal failure who developed end-stage cardiomyopathy. Left venticulography showed severe diffuse hypokinesia and left ventricular ejection fraction was calculated at 12%. Endomyocardial biopsy demonstrated platelike calcium oxalate crystals within the myocardium and the connective tissue, and mild perivascular fibrosis. The patient was first considered for combined liver-heart-kidney transplantation, but as his cardiac function improved slightly with an intensive dialysis program, combined liver and kidney transplantation was performed. Normal cardiac function was demonstrated at 1-year follow-up, and comparative endomyocardial biopsy showed regression of the myocardial oxalate deposits. This case adds stronger clinical, hemodynamic, and histopathological evidence that severe oxalosis cardiomyopathy may be reversed after combined liver and kidney transplantation.
Professionals ; Students ; General public
http://hdl.handle.net/2268/1151

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