Article (Scientific journals)
Abdominal aortic aneurysm.
SakalihasanN, Natzi; Limet, Raymond; Defawe, O. D.
2005In The Lancet, 365 (9470), p. 1577-89
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Keywords :
Aortic Aneurysm, Abdominal/diagnosis/etiology/physiopathology/surgery; Aortic Rupture/diagnosis/prevention & control/surgery; Humans; Risk Factors
Abstract :
[en] Abdominal aortic aneurysms cause 1.3% of all deaths among men aged 65-85 years in developed countries. These aneurysms are typically asymptomatic until the catastrophic event of rupture. Repair of large or symptomatic aneurysms by open surgery or endovascular repair is recommended, whereas repair of small abdominal aortic aneurysms does not provide a significant benefit. Abdominal aortic aneurysm is linked to the degradation of the elastic media of the atheromatous aorta. An inflammatory cell infiltrate, neovascularisation, and production and activation of various proteases and cytokines contribute to the development of this disorder, although the underlying mechanisms are unknown. In this Seminar, we aim to provide an updated review of the pathophysiology, current and new diagnostic procedures, assessment, and treatment of abdominal aortic aneurysm to provide family practitioners with a working knowledge of this disorder.
Disciplines :
Surgery
Author, co-author :
SakalihasanN, Natzi ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie cardio-vasculaire
Limet, Raymond ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie cardio-vasculaire
Defawe, O. D.;  Université de Liège - ULiège > Laboratory of Connective Tissues Biology
Language :
English
Title :
Abdominal aortic aneurysm.
Publication date :
2005
Journal title :
The Lancet
ISSN :
0140-6736
eISSN :
1474-547X
Publisher :
Lancet Publishing Group, London, United Kingdom
Volume :
365
Issue :
9470
Pages :
1577-89
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 13 March 2012

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