Article (Scientific journals)
Pulmonary function changes induced by three regimens of bronchodilating agents in calves with acute respiratory distress syndrome
Genicot, Bruno; Close, Roland; Lindsey, J. K. et al.
1995In Veterinary Record, 137 (8), p. 183-186
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Keywords :
Pulmonary functions; respiratory diseases; calves
Abstract :
[en] Two aerosolised bronchodilators, one sympathomimetic and one parasympatholytic, were tested either alone or in combination for their ability to improve the pulmonary function of double-muscled calves suffering from acute respiratory distress syndrome. In control animals treated with 0.9 per cent saline the parameters of pulmonary function and signs of clinical distress did not change significantly within the hour following the first treatment. Among the other animals, both at one hour and seven days after the first treatment, the most clinical improvement was observed in the animals treated with both bronchodilators and the least in the animals treated with clenbuterol hydrochloride. One hour after the first treatment the respiratory system compliance of the animals treated with ipratropium bromide and the arterial oxygen tension of the animals treated with both bronchodilators were significantly enhanced. After seven days the resistive parameters, the rectal temperature and the respiratory rate were also significantly improved in the animals treated with ipratropium bromide or both bronchodilators whereas only the respiratory rate and rectal temperature were significantly reduced in the animals treated with clenbuterol hydrochloride.
Research center :
Laboratoire d'Investigation fonctionnelle, service de Physiologie
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology
Veterinary medicine & animal health
Author, co-author :
Genicot, Bruno
Close, Roland
Lindsey, J. K.
Lekeux, Pierre ;  Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie
Language :
English
Title :
Pulmonary function changes induced by three regimens of bronchodilating agents in calves with acute respiratory distress syndrome
Publication date :
1995
Journal title :
Veterinary Record
ISSN :
0042-4900
eISSN :
2042-7670
Publisher :
British Veterinary Medicine, London, United Kingdom
Volume :
137
Issue :
8
Pages :
183-186
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
MRW - Ministère de la Région wallonne [BE]
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