Reference : Atmungsmechanik beim Tier. 3. Mitteilung : Methodische und physiologische Aspekte bei de...
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/113973
Atmungsmechanik beim Tier. 3. Mitteilung : Methodische und physiologische Aspekte bei der Anwendung des Impuls-Oszilloresistometrie-Systems (IOS)
English
[en] Mechanics of breathing in animals. Part 3. Methodological and physiological aspects using the impulse oscillometry system (IOS)
Reinhold, Petra [Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterinärmedizin, Bakterielle Tierseuchen und Bekämpfung von Zoonosen, Jena > > > > >]
Steinbach, Günther [> >]
Langenberg, Annelie [> >]
Lekeux, Pierre mailto [Université de Liège - ULg > Département de sciences fonctionnelles > Physiologie - Doyen de la Faculté de Médecine vétérinaire >]
1998
Berliner und Munchener Tierarztliche Wochenschrift
Verlag Paul Parey
111
253-61
International
0005-9366
Berlin
Germany
[en] lung function ; animals ; mechanics of breathing ; forced oscillation technique ; impulse oscillometry ; respiratory impedance
[en] The impulse oscillometry system (IOS) which was originally developed for human medicine was found to be suitable for analysing respiratory mechanics in spontaneously breathing animals. This technique is non-invasive. METHODOLOGICAL ASPECTS: In order to use the IOS-technique in animals, a tightly fitting face mask is necessary. Furthermore, a flexible tube needs to be inserted into the measuring system. While the tube does not influence the measured results significantly, the face mask may affect the measurements. Therefore, its influence on the measured respiratory impedance must be taken into account. To prevent methodological errors, the head and body position of the animal should be standardised during the IOS-measurement. Since the methodological variability of the system is very small, the measuring results are highly reproducible. PHYSIOLOGICAL ASPECTS: In growing subjects, all parameters of respiratory mechanics depend on body weight. Since respiratory physiology is influenced by circadian rhythms, measurements of different days are only comparable when they have been done each day at the same hour. Comparing the respiratory impedance of different animals of similar age and body weight, a considerable inter-individual variability was observed. Due to the low level of physiological intra-individual variability, the method seems to be especially useful for studying influences on the respiratory system (i.e. pharmaceutics, therapeutics) in long-term studies using the same group of subjects.
Researchers ; Professionals
http://hdl.handle.net/2268/113973

There is no file associated with this reference.

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.